Cochrane · systematic review · CD006604

Uterine distension media for outpatient hysteroscopy

Abdallah, KS, Gadalla, MA., Breijer, MC, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
5
No studies
1
Included studies
NR
No studies 1 · 12.5%Ungraded 2 · 25%Very low 0 · 0%Low 4 · 50%Moderate 1 · 12.5%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Saline vs carbon dioxide for uterine distension in outpatient hysteroscopy

Population: women undergoing outpatient hysteroscopy
4 questions
OutcomeEffectEvidenceStatus / GRADE
Tolerability of the procedure
Saline vs carbon dioxide
no estimate extracted9 studies · 1705 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Adverse events and complications
Saline vs carbon dioxide
Peto OR 0.53 [0.32, 0.86]6 studies · 1076 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Quality of hysteroscopic view
Saline vs carbon dioxide
Peto OR 0.51 [0.32, 0.82]5 studies · 1082 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Duration of the procedureassessed in seconds
Saline vs carbon dioxide
no estimate extracted3 studies · 4 participantsUngraded

Warm saline vs room temperature saline for uterine distension in outpatient hysteroscopy

Population: women undergoing outpatient hysteroscopy
4 questions
OutcomeEffectEvidenceStatus / GRADE
Tolerability of the procedure
Warm saline vs room temperature saline
no estimate extracted3 studies · 241 participantsLow
Downgraded: risk of bias
Adverse events and complications
Warm saline vs room temperature saline
no estimate extracted1 study · 100 participantsUngraded
Quality of hysteroscopic view
Warm saline vs room temperature saline
no estimate extractedNRNo studies
Duration of the procedureassessed in seconds
Warm saline vs room temperature saline
no estimate extracted2 studies · 141 participantsLow
Downgraded: risk of bias