What do systematic reviews say?

Postnatal depression · preventing gestational diabetes

Development of subsequent diabetes · preventing gestational diabetes

Duration of continuous positive airway pressure therapy (hours or days) · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome

Duration of neonatal intensive care unit stay (hours or days) · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome

Duration of hospital stay (days) · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome

Seizure freedom · people with juvenile myoclonic epilepsy

Quality of life ‐ not reported · participants with tophi in gout

Serum urate normalisation ‐ not reported · participants with tophi in gout

Function ‐ not reported · participants with tophi in gout

Joint pain reduction ‐ not reported · participants with tophi in gout

Quality of life ‐ not reported · participants with tophi in gout

Serum urate normalisation ‐ not reported · participants with tophi in gout

Function ‐ not reported · participants with tophi in gout

Joint pain reduction ‐ not reported · participants with tophi in gout

Progression of disease (to Fontaine stage III or IV or necessity for intervention (endovascular or surgery)) · intermittent claudication

Side effects of propionyl‐L‐carnitine regimen · intermittent claudication

Ankle brachial index · intermittent claudication

Quality of life · intermittent claudication

HRQOL ‐ not measured · acute gout

Joint pain reduction ‐ not reported · participants with chronic gout and sUA level > 0.36mmol/L