Findings

What do systematic reviews say?

4,929 questions · 15,213 findings · 2,394 reviews

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No studies found 15,213 · 100%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

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BNT162b2 – Pfizer/BioNTech + Fosun Pharma vs placebo

Local reactogenicity events

The review found no eligible studies for this question.

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

NVX‐CoV2373 – Novavax vs placebo

Confirmed SARS‐CoV‐2 infection

The review found no eligible studies for this question.

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

FINLAY‐FR‐2 – Instituto Finlay de Vacunas vs placebo

Confirmed SARS‐CoV‐2 infection

The review found no eligible studies for this question.

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

FINLAY‐FR‐2 – Instituto Finlay de Vacunas vs placebo

Severe or critical COVID‐19

The review found no eligible studies for this question.

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Wait‐list compared with no‐treatment · patients with mental health disorders

The review found no eligible studies for this question.

1 finding from 1 review

Control interventions in randomised trials among people with mental health disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Serious adverse events for all placebos · patients with mental health disorders

The review found no eligible studies for this question.

1 finding from 1 review

Control interventions in randomised trials among people with mental health disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Non‐serious adverse events for all placebos · patients with mental health disorders

The review found no eligible studies for this question.

1 finding from 1 review

Control interventions in randomised trials among people with mental health disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Flowable resin composite vs Fluoride-releasing resin-based sealant

Development of >=1 new carious lesion (caries incidence) · Children who were regular dental attenders with caries-free first or second primary molars (public health service clinic, Brazil)

The review found no eligible studies for this question.

1 finding from 1 review

Sealants for preventing dental caries in primary teeth 2022 · Cochrane All outcomes
No studies reported this outcome.
0 studies
No studies found

Bio-active restorative materials vs Any restorative material or technique

Not applicable (no eligible studies) · Children with carious primary teeth (no pulp therapy)

No eligible RCTs assessed new bio-active restorative materials in carious primary teeth; this is an evidence gap identified by the review.

1 finding from 1 review

Clinical effectiveness of restorative materials for the restoration of carious primary teeth without pulp therapy: a… 2022 All outcomes
The search retrieved no randomized controlled trials on the clinical effectiveness of new bio-active restorative materials for carious primary teeth.
0 studies
No studies found

Responsive / non-responsive complementary feeding (RCF/NRCF) vs Other models of complementary feeding

Choking · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western industrialized countries

No systematic reviews or studies assessed choking risk for RCF or NRCF (only BLW/BLISS); this is an evidence gap.

1 finding from 1 review

Complementary Feeding Caregivers' Practices and Growth, Risk of Overweight/Obesity, and Other Non-Communicable… 2022 All outcomes
Infancy · Outpatient care in Western industrialized (European/Anglo-Saxon) countries
No SRs or studies relevant to the risk of choking were found that included NRCF or RCF approaches other than those specifically defined as BLW or BLISS.
0 studies
No studies found

Autopolymerised sealant vs Light polymerised sealant

Progression of non-cavitated enamel caries · Children with sound primary molars, aged 2-4 years (municipal dental clinics or hospital paediatric clinics, Denmark)

The review found no eligible studies for this question.

1 finding from 1 review

Sealants for preventing dental caries in primary teeth 2022 · Cochrane All outcomes
No studies reported on this outcome.
0 studies
No studies found

Professional oral care vs Usual oral care

Change in systemic antibiotic use · Residents of nursing homes and other long-term care facilities

The review found no eligible studies for this question.

1 finding from 1 review

Oral care measures for preventing nursing home‐acquired pneumonia 2022 · Cochrane All outcomes
No studies measured change in systemic antibiotic use.
0 studies
No studies found

Antibiotic prophylaxis before dental procedure vs placebo or no prophylaxis

Adverse effects of antibiotics · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for preventing bacterial endocarditis following dental procedures 2022 · Cochrane All outcomes
Adverse effects of antibiotics | No data reported | 248 (1 study) | - | -
0 studies
No studies found

Combined antiretroviral therapy (cART) vs Monotherapy or dual antiretroviral therapy

Oral hairy leukoplakia prevalence · Children and adolescents (<18 years) living with HIV (CLWH)

No eligible studies compared oral hairy leukoplakia between different ART regimens.

1 finding from 1 review

Impact of Antiretroviral Therapy on Oral Health among Children Living with HIV: A Systematic Review and Meta-Analysis. 2022 All outcomes
Hospitals and AIDS outpatient centres in India, Brazil, and several Asian countries
No eligible studies compared oral hairy leukoplakia between CLWH on different ART medications.
0 studies
No studies found

Traditional screening (referral card given if the inspecting dentist judges the child needs to see a dentist) vs No screening

Adverse events · School children (aged 4 to 15 years), primary and secondary schools in the UK and India

The review found no eligible studies for this question.

1 finding from 1 review

School dental screening programmes for oral health 2022 · Cochrane All outcomes
Adverse events: Not reported (Summary of findings 1).
0 studies
No studies found

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

Diabetic complications · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Treatment of periodontitis for glycaemic control in people with diabetes mellitus 2022 · Cochrane All outcomes
3-4 months
Included studies did not report data on diabetic complications (some reported medication changes only)
0 studies
No studies found

Food and nonalcoholic beverage marketing (exposure) vs No, less, or less powerful food marketing

Diet-related noncommunicable diseases · Children and adolescents (general population, aged under 20 years)

No eligible studies were found.

1 finding from 1 review

Association of Food and Nonalcoholic Beverage Marketing With Children and Adolescents' Eating Behaviors and Health: A… 2022 All outcomes
Predominantly high-income countries
No studies were found with relevant data on diet-related noncommunicable diseases or validated surrogate indicators.
0 studies
No studies found

Antibiotic prophylaxis before dental procedure vs placebo or no prophylaxis

Cost implications of antibiotic provision · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for preventing bacterial endocarditis following dental procedures 2022 · Cochrane All outcomes
The study did not provide any data on mortality, adverse events requiring hospitalisation, adverse effects of antibiotics or cost implications of treatment.
0 studies
No studies found

Any preprocedural mouth rinse vs Placebo, no rinsing or control

Costs · People undergoing aerosol-generating procedures (AGPs) in a dental setting

The review found no eligible studies for this question.

1 finding from 1 review

Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental healthcare… 2022 · Cochrane All outcomes
No included study reported cost.
0 studies
No studies found

Fluoride-containing dental care products (mainly fluoride toothpaste) vs Dietary fluoride sources (drinking water, beverages, food)

Contribution of dental care products to total fluoride exposure · Pregnant and lactating women

No study has explored the contribution of dental care products to total fluoride exposure in pregnant and lactating women.

1 finding from 1 review

Fluoride Intake Through Dental Care Products: A Systematic Review. 2022 All outcomes
no estimate extracted
0 studies
No studies found