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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Hypertonic saline vs mannitol
FEV1: long‐term · adults and children with cystic fibrosis
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline vs mannitol
LCI · adults and children with cystic fibrosis
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline vs mannitol
Mortality · adults and children with cystic fibrosis
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline 3% to 7% vs isotonic saline
Mortality · adults and children with cystic fibrosis (stable lung disease)
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline vs mannitol
Pulmonary exacerbations · adults and children with cystic fibrosis
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline 7% vs xylitol
FEV1 (% predicted) change from baseline, long‐term · adults with cystic fibrosis
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline 7% vs xylitol
LCI · adults with cystic fibrosis
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline 7% vs xylitol
Mortality · adults with cystic fibrosis
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline 7% vs xylitol
Measures of sputum clearance · adults with cystic fibrosis
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline 7% vs hypertonic saline 3%
FEV1 (% predicted) change from baseline, long‐term · children with cystic fibrosis
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline 7% vs hypertonic saline 3%
LCI · children with cystic fibrosis
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline 7% vs hypertonic saline 3%
Mortality · children with cystic fibrosis
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline 7% vs hypertonic saline 3%
Measures of sputum clearance · children with cystic fibrosis
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline 7% vs hypertonic saline 3%
Pulmonary exacerbations · children with cystic fibrosis
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline 7% vs hypertonic saline 3%
Adverse events · children with cystic fibrosis
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Hypertonic saline 3% to 7% vs isotonic saline
FEV1 (% predicted) change from baseline, long‐term · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
Nebulised hypertonic saline for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
Transfusions (during hospital stay) ‐ not reported · cancer surgery
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
DVT (up to 90 days) ‐ not reported · cardiovascular (no bypass) surgeries
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
Volume (PPT) (during hospital stay) ‐ not reported · cancer surgery
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
Mortality (up to 90 days) ‐ not reported · obstetric surgeries
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
DVT (up to 90 days) ‐ not reported · obstetric surgeries
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
Infection (up to 90 days) ‐ not reported · obstetric surgeries
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
MI (up to 90 days) ‐ not reported · obstetric surgeries
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
CVA (stroke) (up to 90 days) ‐ not reported · obstetric surgeries
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
MI (up to 90 days) ‐ not reported · orthopaedic (hip)
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
Mortality (up to 90 days) ‐ not reported · orthopaedic (knee)
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
Mortality (up to 90 days) ‐ not reported · orthopaedic (spinal)
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
DVT (up to 90 days) ‐ not reported · orthopaedic (spinal)
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
MI (up to 90 days) ‐ not reported · orthopaedic (spinal)
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
CVA (stroke) (up to 90 days) ‐ not reported · orthopaedic (spinal)
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
MI (up to 90 days) ‐ not reported · cancer surgery
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
CVA (stroke) (up to 90 days) ‐ not reported · orthopaedic (mixed)
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Cell salvage vs no cell salvage
CVA (stroke) (up to 90 days) ‐ not reported · cancer surgery
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery (2023) · Cochrane
no estimate extractedNRNo studies
Tissue plasminogen activator (t‐PA) vs standard treatment
Quality of life measures at 1 month · people with acute non‐arteritic CRAO
Interventions for acute non‐arteritic central retinal artery occlusion (2023) · Cochrane
no estimate extractedNRNo studies
Bisphosphonates vs placebo
BMD: % change in BMD at the hip or femur · children with cystic fibrosis who have not had a lung transplant
Bisphosphonates for osteoporosis in people with cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Bisphosphonates vs placebo
QoL · children with cystic fibrosis who have not had a lung transplant
Bisphosphonates for osteoporosis in people with cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Bisphosphonates vs no bisphosphonates
QoL · adults with cystic fibrosis who have had a lung transplant
Bisphosphonates for osteoporosis in people with cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
CCPT vs extrapulmonary mechanical percussion
Mucus weight · children and adults with cystic fibrosis
Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
CCPT vs ACBT
Respiratory exacerbations: time to first exacerbation · children and adults with cystic fibrosis
Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
CCPT vs ACBT
QoL: change in CFQ score · children and adults with cystic fibrosis
Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
CCPT vs ACBT
Mucus weight · children and adults with cystic fibrosis
Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
CCPT vs O‐PEP devices
Respiratory exacerbations: number of respiratory exacerbations per year · children and adults with cystic fibrosis
Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
CCPT vs AD
Respiratory exacerbations: number of respiratory exacerbations per year · children and adolescents with cystic fibrosis
Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
CCPT vs AD
QoL · children and adolescents with cystic fibrosis
Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
CCPT vs AD
Mucus weight · children and adolescents with cystic fibrosis
Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
CCPT vs exercise
FEV1 · children and young adults with cystic fibrosis
Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
CCPT vs exercise
FVC · children and young adults with cystic fibrosis
Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
CCPT vs exercise
FEF25–75 · children and young adults with cystic fibrosis
Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
CCPT vs exercise
Respiratory exacerbations: number of respiratory exacerbations per year · children and young adults with cystic fibrosis
Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
CCPT vs PEP
Respiratory exacerbations: number of respiratory exacerbations per year · children and adults with cystic fibrosis
Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies