Cochrane · systematic review · CD001989

Interventions for acute non‐arteritic central retinal artery occlusion

Lin, JC, Song, S, Ng, SM, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
2
No studies
1
Included studies
NR
No studies 1 · 33.3%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 66.7%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Tissue plasminogen activator (t‐PA) compared with standard treatment for acute non‐arteritic central retinal artery occlusion (CRAO)

Population: people with acute non‐arteritic CRAO
3 questions
OutcomeEffectEvidenceStatus / GRADE
Mean change in BCVA at 1 month (logMAR)
Tissue plasminogen activator (t‐PA) vs standard treatment
no estimate extracted2 studies · 98 participantsLow
Downgraded: imprecision
Quality of life measures at 1 month
Tissue plasminogen activator (t‐PA) vs standard treatment
no estimate extractedNRNo studies
Adverse events at 1 month
Tissue plasminogen activator (t‐PA) vs standard treatment
no estimate extracted3 studies · 146 participantsLow
Downgraded: imprecision