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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

726 questions in 98 reviews · Pregnancy and Childbirth

current versions
No studies 726 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Fetal growth (biometry) + umbilical artery Doppler vs fetal growth
Birth less than 28 weeks · women with twin pregnancies were randomised from 25 weeks
Regimens of ultrasound surveillance for twin pregnancies for improving outcomes (2017) · Cochrane
no estimate extractedNRNo studies
Assessment vs direct admission
Neonatal admission to special care · healthy pregnant women
Assessment and support during early labour for improving birth outcomes (2017) · Cochrane
no estimate extractedNRNo studies
Any supplement containing iodine vs same supplement without iodine or no treatment/placebo (child outcomes)
Child adverse effect: hyperthyroidism · women during the preconception, pregnancy and postpartum period
Iodine supplementation for women during the preconception, pregnancy and postpartum period (2017) · Cochrane
no estimate extractedNRNo studies
Insulin Aspart (+ NPH) vs human insulin (+ NPH insulin)
Macrosomia · pregnant women with pre‐existing diabetes
Different insulin types and regimens for pregnant women with pre‐existing diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Insulin Aspart (+ NPH) vs human insulin (+ NPH insulin)
Perinatal death · pregnant women with pre‐existing diabetes
Different insulin types and regimens for pregnant women with pre‐existing diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Insulin Aspart (+ NPH) vs human insulin (+ NPH insulin)
Pre‐eclampsia · pregnant women with pre‐existing diabetes
Different insulin types and regimens for pregnant women with pre‐existing diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Insulin Aspart (+ NPH) vs human insulin (+ NPH insulin)
Caesarean section · pregnant women with pre‐existing diabetes
Different insulin types and regimens for pregnant women with pre‐existing diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Insulin Aspart (+ NPH) vs human insulin (+ NPH insulin)
Fetal anomaly · pregnant women with pre‐existing diabetes
Different insulin types and regimens for pregnant women with pre‐existing diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Insulin Aspart (+ NPH) vs human insulin (+ NPH insulin)
Birth trauma including shoulder dystocia, nerve palsy and fracture · pregnant women with pre‐existing diabetes
Different insulin types and regimens for pregnant women with pre‐existing diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Insulin Aspart (+ NPH) vs human insulin (+ NPH insulin)
Composite outcome measure of neonatal morbidity · pregnant women with pre‐existing diabetes
Different insulin types and regimens for pregnant women with pre‐existing diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Oral anti‐diabetic pharmacological therapies vs placebo ‐ neonatal outcomes
Death or serious morbidity composite ‐ not reported · infants of women diagnosed with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Oral anti‐diabetic pharmacological therapies vs placebo ‐ neonatal outcomes
Adiposity (neonate, child, adult) ‐ not measured · infants of women diagnosed with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Oral anti‐diabetic pharmacological therapies vs placebo ‐ neonatal outcomes
Diabetes (child, adult) ‐ not measured · infants of women diagnosed with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Oral anti‐diabetic pharmacological therapies vs placebo ‐ neonatal outcomes
Neurosensory disability in later childhood ‐ not measured · infants of women diagnosed with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Metformin vs glibenclamide ‐ maternal outcomes
Development of type 2 diabetes ‐ not measured · women diagnosed with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Metformin vs glibenclamide ‐ maternal outcomes
Return to pre‐pregnancy weight ‐ not measured · women diagnosed with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Metformin vs glibenclamide ‐ maternal outcomes
Postnatal depression ‐ not measured · women diagnosed with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Metformin vs glibenclamide ‐ neonatal outcomes
Adiposity ‐ not measured · Infants of women diagnosed with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Metformin vs glibenclamide ‐ neonatal outcomes
Diabetes ‐ not measured · Infants of women diagnosed with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Metformin vs glibenclamide ‐ neonatal outcomes
Neurosensory disability in later childhood ‐ not measured · Infants of women diagnosed with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Glibenclamide vs acarbose ‐ maternal outcomes
Hypertensive disorders of pregnancy ‐ not reported · women diagnosed with gestational diabetes; 11 to 33 weeks' gestation; singleton pregnancy
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Oral anti‐diabetic pharmacological therapies vs placebo ‐ maternal outcomes
Development of type 2 diabetes ‐ not measured · women diagnosed with gestational diabetes; 24‐30 weeks' gestation; singleton pregnancy.
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Glibenclamide vs acarbose ‐ maternal outcomes
Development of type 2 diabetes ‐ not reported · women diagnosed with gestational diabetes; 11 to 33 weeks' gestation; singleton pregnancy
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Glibenclamide vs acarbose ‐ maternal outcomes
Perineal trauma ‐ not reported · women diagnosed with gestational diabetes; 11 to 33 weeks' gestation; singleton pregnancy
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Glibenclamide vs acarbose ‐ maternal outcomes
Return to pre‐pregnancy weight ‐ not reported · women diagnosed with gestational diabetes; 11 to 33 weeks' gestation; singleton pregnancy
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Glibenclamide vs acarbose ‐ maternal outcomes
Postnatal depression ‐ not reported · women diagnosed with gestational diabetes; 11 to 33 weeks' gestation; singleton pregnancy
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Glibenclamide vs acarbose ‐ maternal outcomes
Induction of labour ‐ not reported · women diagnosed with gestational diabetes; 11 to 33 weeks' gestation; singleton pregnancy
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Glibenclamide vs acarbose ‐ neonatal outcomes
Death or serious morbidity composite ‐ not reported · women with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Glibenclamide vs acarbose ‐ neonatal outcomes
Adiposity ‐ not reported · women with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Glibenclamide vs acarbose ‐ neonatal outcomes
Diabetes ‐ not reported · women with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Glibenclamide vs acarbose ‐ neonatal outcomes
Neurosensory disability in later childhood ‐ not reported · women with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Oral anti‐diabetic pharmacological therapies vs placebo ‐ maternal outcomes
Return to pre‐pregnancy weight ‐ not measured · women diagnosed with gestational diabetes; 24‐30 weeks' gestation; singleton pregnancy.
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Oral anti‐diabetic pharmacological therapies vs placebo ‐ maternal outcomes
Postnatal depression ‐ not measured · women diagnosed with gestational diabetes; 24‐30 weeks' gestation; singleton pregnancy.
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Oral anti‐diabetic pharmacological therapies vs placebo ‐ neonatal outcomes
Perinatal mortality · infants of women diagnosed with gestational diabetes
Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Lifestyle vs control ‐ Neonatal and later outcomes
Adiposity (adult) not measured · Women with gestational diabetes
Lifestyle interventions for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Lifestyle vs control ‐ Neonatal and later outcomes
Diabetes (type 2) (child) ‐ not measured · Women with gestational diabetes
Lifestyle interventions for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Lifestyle vs control ‐ Neonatal and later outcomes
Diabetes (type 2) (adult) ‐ not measured · Women with gestational diabetes
Lifestyle interventions for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Lifestyle vs control ‐ Neonatal and later outcomes
Neurosensory disability (child) ‐ not measured · Women with gestational diabetes
Lifestyle interventions for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Lifestyle vs control ‐ Neonatal and later outcomes
Neurosensory disability (adult) ‐ not measured · Women with gestational diabetes
Lifestyle interventions for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Psychosocial effects of bed rest (depression, anxiety, stress) · women with multiple pregnancy
Bed rest with and without hospitalisation in multiple pregnancy for improving perinatal outcomes (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Psychosocial effects of bed rest (depression, anxiety, stress) · women with multiple pregnancy
Bed rest with and without hospitalisation in multiple pregnancy for improving perinatal outcomes (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Low birthweight (less than 2500 g) ‐ assuming independence between twins/triplets · women with multiple pregnancy
Bed rest with and without hospitalisation in multiple pregnancy for improving perinatal outcomes (2017) · Cochrane
no estimate extractedNRNo studies
Insulin vs anti‐diabetic agent
Childhood/adulthood diabetes (type 1, type 2) ‐ not reported · Infants of women with gestational diabetes.
Insulin for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Insulin vs anti‐diabetic agent
Perineal trauma/tearing ‐ not measured · the treatment of women (maternal outcomes) with gestational diabetes
Insulin for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Insulin vs anti‐diabetic agent
Postnatal depression ‐ not reported · the treatment of women (maternal outcomes) with gestational diabetes
Insulin for the treatment of women with gestational diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Exercise vs control
Adiposity ‐ not reported · pregnant women with gestational diabetes
Exercise for pregnant women with gestational diabetes for improving maternal and fetal outcomes (2017) · Cochrane
no estimate extractedNRNo studies
Exercise vs control
Diabetes (type 1, type 2) ‐ not reported · pregnant women with gestational diabetes
Exercise for pregnant women with gestational diabetes for improving maternal and fetal outcomes (2017) · Cochrane
no estimate extractedNRNo studies
Exercise vs control
Neurosensory disability · pregnant women with gestational diabetes
Exercise for pregnant women with gestational diabetes for improving maternal and fetal outcomes (2017) · Cochrane
no estimate extractedNRNo studies
Exercise vs control
Development of type 2 diabetes ‐ not measured · pregnant women with gestational diabetes
Exercise for pregnant women with gestational diabetes for improving maternal and fetal outcomes (2017) · Cochrane
no estimate extractedNRNo studies
Exercise vs control
Perineal trauma/tearing ‐ not measured · pregnant women with gestational diabetes
Exercise for pregnant women with gestational diabetes for improving maternal and fetal outcomes (2017) · Cochrane
no estimate extractedNRNo studies