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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

651 questions in 62 reviews · Wounds

current versions
No studies 651 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement vs placebo
Ulcer healing (absolute change in individual parameters of ulcer dimensions over time) · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
Subcuticular sutures vs surgical tapes
Cosmesis of scar · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
no estimate extractedNRNo studies
Subcuticular sutures vs surgical tapes
Patient satisfaction · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
no estimate extractedNRNo studies
Subcuticular sutures vs surgical zippers
Patient satisfaction · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
no estimate extractedNRNo studies
Electrical stimulation (plus standard care) vs sham/no ES (plus standard care)
Quality of life (QoL) · people with pressure ulcers
Electrical stimulation for treating pressure ulcers (2020) · Cochrane
no estimate extractedNRNo studies
Perioperative antibiotics vs placebo or no antibiotic
Cost of care · breast cancer surgery
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane
no estimate extractedNRNo studies
Perioperative antibiotics vs placebo or no antibiotic
Adverse reactions to treatment · breast cancer surgery
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane
no estimate extractedNRNo studies
Perioperative antibiotics vs placebo or no antibiotic
Time to onset of infection · breast cancer surgery
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane
no estimate extractedNRNo studies
Perioperative antibiotics vs placebo or no antibiotic
Readmission to hospital · breast cancer surgery
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane
no estimate extractedNRNo studies
Ramstadius pressure ulcer risk assessment vs pressure ulcer risk assessment using clinical judgement
Time to ulcer development Pressure ulcer prevalence · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Waterlow pressure ulcer risk assessment vs Ramstadius pressure ulcer risk assessment
Time to ulcer development Pressure ulcer prevalence · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Braden pressure ulcer risk assessment and training vs pressure ulcer risk assessment using clinical judgement and training
Severity of new pressure ulcers Time to ulcer development Pressure ulcer prevalence · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Braden pressure ulcer risk assessment and training vs pressure ulcer risk assessment using clinical judgement alone
Severity of new pressure ulcers Time to ulcer development Pressure ulcer prevalence · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Waterlow pressure ulcer risk assessment vs pressure ulcer risk assessment using clinical judgement
Time to ulcer development Pressure ulcer prevalence · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Primary closure vs no closure
Time to complete wound healing · patients with traumatic wounds due to dog bite
​Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite (2019) · Cochrane
no estimate extractedNRNo studies
Primary closure vs no closure
Proportion of wounds which were infection‐free · patients with traumatic wounds due to dog bite
​Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite (2019) · Cochrane
no estimate extractedNRNo studies
Primary closure vs delayed closure
Time to complete wound healing · patients with traumatic wounds due to dog bite
​Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite (2019) · Cochrane
no estimate extractedNRNo studies
Primary closure vs delayed closure
Proportion of wounds which were infection‐free · patients with traumatic wounds due to dog bite
​Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite (2019) · Cochrane
no estimate extractedNRNo studies
Primary closure vs delayed closure
Cosmesis using validated cosmetic outcome score at 4 weeks · patients with traumatic wounds due to dog bite
​Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite (2019) · Cochrane
no estimate extractedNRNo studies
Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure
Quality of life · participants with venous leg ulcers
Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure
Pain · participants with venous leg ulcers
Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery
Time to complete healing · participants with venous leg ulcers
Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery
Quality of life · participants with venous leg ulcers
Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery
Pain · participants with venous leg ulcers
Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone
Time to complete healing · participants with venous leg ulcers
Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone
Quality of life · participants with venous leg ulcers
Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone
Adverse events · participants with venous leg ulcers
Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone
Pain · participants with venous leg ulcers
Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure
Time to complete healing · participants with venous leg ulcers
Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Rigid dressings vs soft dressings
Patient comfort · people who had undergone transtibial amputations
Rigid dressings versus soft dressings for transtibial amputations (2019) · Cochrane
no estimate extractedNRNo studies
Rigid dressings vs soft dressings
Quality of life · people who had undergone transtibial amputations
Rigid dressings versus soft dressings for transtibial amputations (2019) · Cochrane
no estimate extractedNRNo studies
Rigid dressings vs soft dressings
Cost · people who had undergone transtibial amputations
Rigid dressings versus soft dressings for transtibial amputations (2019) · Cochrane
no estimate extractedNRNo studies
Silicone dressing vs no dressing
Adverse events · individuals at risk of pressure ulcer development
Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
Other dressing vs control
Adverse events · individuals at risk of pressure ulcer development
Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
NPWT vs dressings
Adverse events · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
NPWT vs dressings
Cost‐effectiveness · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
Low‐pressure vs high‐pressure NPWT
Proportion of wounds healed · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
Low‐pressure vs high‐pressure NPWT
Time to ulcer healing · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
Low‐pressure vs high‐pressure NPWT
Amputation · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
Low‐pressure vs high‐pressure NPWT
Cost‐effectiveness · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
Low‐pressure vs high‐pressure NPWT
Wound recurrence · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
NPWT vs dressings
Cost‐effectiveness · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
NPWT vs dressings
Wound recurrence · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
Training, monitoring and observation vs monitoring and observation
Severity of new pressure ulcers · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
Training, monitoring and observation vs monitoring and observation
Patient‐reported outcomes · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
Training, monitoring and observation vs monitoring and observation
Carer‐reported outcomes · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
Training, monitoring and observation vs observation alone
Change in health professionals' knowledge · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
Training, monitoring and observation vs observation alone
Change in health professionals' clinical behaviour · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
Training, monitoring and observation vs observation alone
Severity of new pressure ulcers · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
Training, monitoring and observation vs observation alone
Patient‐reported outcomes · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies