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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

587 questions in 116 reviews · Eyes and Vision

current versions
No studies 587 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Summary of findings: intracanalicular vs silicone punctal plugs
Adverse events · adults with dry eye syndrome
Punctal occlusion for dry eye syndrome (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings: autologous serum vs saline
Fluorescein staining Range of scale: 0‐9, where a higher score is worse · participants with dry eye
Autologous serum eye drops for dry eye (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings: autologous serum vs saline
Tear film break‐up time · participants with dry eye
Autologous serum eye drops for dry eye (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings: autologous serum vs saline
Schirmer’s test Score < 4 mm indicates severe dry eye · participants with dry eye
Autologous serum eye drops for dry eye (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings: autologous serum vs saline
Adverse events · participants with dry eye
Autologous serum eye drops for dry eye (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings: autologous serum vs artificial tears
Tear hyperosmolarity · participants with dry eye
Autologous serum eye drops for dry eye (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings: autologous serum vs artificial tears
Adverse events · participants with dry eye
Autologous serum eye drops for dry eye (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings: autologous serum vs saline
Participant‐reported symptoms · participants with dry eye
Autologous serum eye drops for dry eye (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings: autologous serum vs saline
Tear hyperosmolarity · participants with dry eye
Autologous serum eye drops for dry eye (2017) · Cochrane
no estimate extractedNRNo studies
Topical NSAIDs vs control
Participant‐reported pain intensity reduction of 30%/50% or greater at 24 hours · analgesia in traumatic corneal abrasions
Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions (2017) · Cochrane
no estimate extractedNRNo studies
Topical NSAIDs vs control
Use of rescue oral analgesia at 48/72 hours · analgesia in traumatic corneal abrasions
Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions (2017) · Cochrane
no estimate extractedNRNo studies
Smaller coaxial microincision cataract surgery (C‐MICS) vs standard phacoemulsification
Adverse events · adults with age‐related cataract
Different‐sized incisions for phacoemulsification in age‐related cataract (2017) · Cochrane
no estimate extractedNRNo studies
Smaller coaxial microincision cataract surgery (C‐MICS) vs standard phacoemulsification
Quality of life · adults with age‐related cataract
Different‐sized incisions for phacoemulsification in age‐related cataract (2017) · Cochrane
no estimate extractedNRNo studies
Smaller coaxial microincision cataract surgery (C‐MICS) vs larger C‐MICS
Adverse events · adults with age‐related cataract
Different‐sized incisions for phacoemulsification in age‐related cataract (2017) · Cochrane
no estimate extractedNRNo studies
Smaller coaxial microincision cataract surgery (C‐MICS) vs larger C‐MICS
Quality of life · adults with age‐related cataract
Different‐sized incisions for phacoemulsification in age‐related cataract (2017) · Cochrane
no estimate extractedNRNo studies
Biaxial microincision cataract surgery (B‐MICS) vs standard phacoemulsification
Adverse events · adults with age‐related cataract
Different‐sized incisions for phacoemulsification in age‐related cataract (2017) · Cochrane
no estimate extractedNRNo studies
Biaxial microincision cataract surgery (B‐MICS) vs standard phacoemulsification
Quality of life · adults with age‐related cataract
Different‐sized incisions for phacoemulsification in age‐related cataract (2017) · Cochrane
no estimate extractedNRNo studies
Larger coaxial microincision cataract surgery (C‐MICS) vs standard phacoemulsification
Quality of life · adults with age‐related cataract
Different‐sized incisions for phacoemulsification in age‐related cataract (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings for NSAIDs plus corticosteroids vs corticosteroids alone
Proportion of participants with best‐corrected visual acuity of 20/40 1 week · people who received phacoemulsification
Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after… (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings for NSAIDs plus corticosteroids vs corticosteroids alone
Time to cessation of treatment · people who received phacoemulsification
Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after… (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings for NSAIDs plus corticosteroids vs corticosteroids alone
Adverse events · people who received phacoemulsification
Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after… (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings for NSAIDs plus corticosteroids vs corticosteroids alone
Economic outcomes · people who received phacoemulsification
Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after… (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings for NSAIDs vs corticosteroids
Proportion of participants with best‐corrected visual acuity of 20/40 1 week · people who received phacoemulsification
Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after… (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings for NSAIDs vs corticosteroids
Time to cessation of treatment · people who received phacoemulsification
Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after… (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings for NSAIDs vs corticosteroids
Adverse events · people who received phacoemulsification
Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after… (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings for NSAIDs vs corticosteroids
Economic outcomes · people who received phacoemulsification
Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after… (2017) · Cochrane
no estimate extractedNRNo studies
Summary of findings for NSAIDs plus corticosteroids vs corticosteroids alone
Intraocular inflammation measured by anterior chamber cell and flare 1 week · people who received phacoemulsification
Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after… (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Proportion of participants with IOP < 21 mmHg at 1 year' · participants with glaucoma or ocular hypertension
Topical medication instillation techniques for glaucoma (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Mean IOP change from baseline at 1 year' · participants with glaucoma or ocular hypertension
Topical medication instillation techniques for glaucoma (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Participant‐reported outcomes related to the ease, convenience, and comfort of instillation at 1 year' · participants with glaucoma or ocular hypertension
Topical medication instillation techniques for glaucoma (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Physiologic measurements of systemic absorption at 1 year' · participants with glaucoma or ocular hypertension
Topical medication instillation techniques for glaucoma (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Escalation of therapy at 1 year' · participants with glaucoma or ocular hypertension
Topical medication instillation techniques for glaucoma (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Mean change in visual fields at 1 year' · participants with glaucoma or ocular hypertension
Topical medication instillation techniques for glaucoma (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events at 1 year' · participants with glaucoma or ocular hypertension
Topical medication instillation techniques for glaucoma (2017) · Cochrane
no estimate extractedNRNo studies
Brimonidine vs apraclonidine
IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP
Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane
no estimate extractedNRNo studies
Brimonidine vs apraclonidine
IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP
Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane
no estimate extractedNRNo studies
Brimonidine vs apraclonidine
Mean change in IOP from pre‐LTP between 2 and 24 hours · people with glaucoma receiving LTP
Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane
no estimate extractedNRNo studies
Brimonidine vs apraclonidine
Adverse events ‐ during study period · people with glaucoma receiving LTP
Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane
no estimate extractedNRNo studies
Apraclonidine vs pilocarpine
IOP increase of ≥ 5 mmHg within 2 hours · people with glaucoma receiving LTP
Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane
no estimate extractedNRNo studies
Apraclonidine vs pilocarpine
IOP increase of ≥ 10 mmHg within 2 hours · people with glaucoma receiving LTP
Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane
no estimate extractedNRNo studies
Apraclonidine vs pilocarpine
Adverse events ‐ during study period · people with glaucoma receiving LTP
Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane
no estimate extractedNRNo studies
Medication given before LTP vs the same medication given after LTP
IOP increase of ≥ 5 mmHg within 2 hours · people with glaucoma receiving LTP
Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane
no estimate extractedNRNo studies
Medication given before LTP vs the same medication given after LTP
IOP increase of ≥ 10 mmHg within 2 hours · people with glaucoma receiving LTP
Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane
no estimate extractedNRNo studies
Medication given before LTP vs the same medication given after LTP
Mean change in IOP from pre‐LTP within 2 hours · people with glaucoma receiving LTP
Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane
no estimate extractedNRNo studies
Medication given before LTP vs the same medication given after LTP
Adverse events ‐ during study period · people with glaucoma receiving LTP
Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane
no estimate extractedNRNo studies
Brimonidine vs apraclonidine
IOP increase of ≥ 10 mmHg within 2 hours · people with glaucoma receiving LTP
Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs topical antibiotics plus warm compresses
Participants who required surgical incision and drainage after the treatment period or seven days after diagnosis · people with acute hordeolum
Acupuncture for acute hordeolum (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs topical antibiotics plus warm compresses
Participants experiencing the occurrence of a chalazion after the treatment period or seven days after diagnosis · people with acute hordeolum
Acupuncture for acute hordeolum (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs topical antibiotics plus warm compresses
Participants experiencing the recurrence of a hordeolum within six months and one year · people with acute hordeolum
Acupuncture for acute hordeolum (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs topical antibiotics plus warm compresses
Participants with a secondary hordeolum during or after the treatment period and seven days after diagnosis · people with acute hordeolum
Acupuncture for acute hordeolum (2017) · Cochrane
no estimate extractedNRNo studies