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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

191 questions in 40 reviews · cluster CL0369

current versions
No studies 1 · 0.5%Ungraded 190 · 99.5%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Water samples with fluoride concentration below the acceptable range
External control of fluoridation in the public water supplies of Brazilian cities as a strategy against… (2021)
Prevalence 45.0 [26.1, 64.7]12 studiesUngraded
Intervention NR
Water samples with fluoride concentration above the acceptable range
External control of fluoridation in the public water supplies of Brazilian cities as a strategy against… (2021)
Prevalence 6.712 studiesUngraded
Intervention NR
Water samples with fluoride concentration below the acceptable range · Region: South Brazil
External control of fluoridation in the public water supplies of Brazilian cities as a strategy against… (2021)
Prevalence 32.4 [7.1, 65.3]NRUngraded
Intervention NR
Water samples with fluoride concentration above the acceptable range · Region: South Brazil
External control of fluoridation in the public water supplies of Brazilian cities as a strategy against… (2021)
Prevalence 12.7 [0.5, 36.6]NRUngraded
Intervention NR
Relative abundance of Veillonella spp. · Sensitivity analysis excluding 2 low-quality studies [12,17]
Meta-Analysis Using NGS Data: The Veillonella Species in Dental Caries. (2021)
MD 2.07 [-2.44, 6.58]4 studiesUngraded
Intervention NR
Water samples with fluoride concentration outside the acceptable range · Region: South Brazil
External control of fluoridation in the public water supplies of Brazilian cities as a strategy against… (2021)
Prevalence 50.7 [40.7, 60.6]NRUngraded
Intervention NR
Anatomic form success rate · Random assignment: No/Incorrect
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.895 [0.817, 0.942]14 studiesUngraded
Intervention NR
Anatomic form success rate · Use of cavity conditioner: No
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.908 [0.824, 0.954]13 studiesUngraded
Intervention NR
Anatomic form success rate · Material type: High-viscosity glass ionomer cement (HVGIC)
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.759 [0.586, 0.875]6 studiesUngraded
Intervention NR
Anatomic form success rate · Reporting bias: No
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.892 [0.829, 0.932]21 studiesUngraded
Intervention NR
Anatomic form success rate · Use of coat: Yes
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.785 [0.608, 0.896]5 studiesUngraded
Intervention NR
Anatomic form success rate · Study design: Nonrandomized controlled trial
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.844 [0.731, 0.916]10 studiesUngraded
Intervention NR
Microleakage/infiltration index: Er,Cr:YSGG vs traditional bur · Geraldo-Martins 2013 (excluded from meta-analysis; higher microleakage with Er,Cr:YSGG)
Does Er,Cr:YSGG reduce the microleakage of restorations when used for cavity preparation? A systematic… (2020)
Qualitative NR [NR, NR]1 studyUngraded
Intervention NR
Anatomic form success rate · Cavity form: Atraumatic restorative treatment (ART)
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.749 [0.606, 0.853]6 studiesUngraded
Intervention NR
Anatomic form success rate · Random assignment: Correct
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.912 [0.809, 0.962]10 studiesUngraded
Intervention NR
Anatomic form success rate · Study design: Noncontrolled trial
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.950 [0.867, 0.982]4 studiesUngraded
Intervention NR
Anatomic form success rate · Material type: Resin-modified glass ionomer cement (RMGIC)
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.934 [0.848, 0.973]5 studiesUngraded
Intervention NR
Anatomic form success rate · Material type: Resin-based material + self-etching adhesion
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.926 [0.829, 0.970]6 studiesUngraded
Intervention NR
Anatomic form success rate · Financial source: Public
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.919 [0.846, 0.959]10 studiesUngraded
Intervention NR
Anatomic form success rate · Financial source: Private or mixed
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.850 [0.678, 0.939]5 studiesUngraded
Intervention NR
Anatomic form success rate · Assessor blinding (triple-blind): Yes
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.852 [0.760, 0.912]14 studiesUngraded
Intervention NR
Anatomic form success rate · Use of coat: No
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.916 [0.808, 0.966]6 studiesUngraded
Intervention NR
Anatomic form success rate · Material type: Resin-based material + total-etching adhesion
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.919 [0.821, 0.966]7 studiesUngraded
Intervention NR
Anatomic form success rate · Use of cavity conditioner: Yes
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.896 [0.779, 0.955]9 studiesUngraded
Intervention NR
Anatomic form success rate · Reporting bias: Yes
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.964 [0.828, 0.994]3 studiesUngraded
Intervention NR
Anatomic form success rate · Study design: Randomized controlled trial
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.907 [0.806, 0.958]10 studiesUngraded
Intervention NR
Anatomic form success rate · Assessor blinding (triple-blind): No
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.943 [0.886, 0.972]10 studiesUngraded
Intervention NR
Anatomic form success rate · Cavity form: Conventional cavity design
Success rate of proximal tooth-coloured direct restorations in primary teeth at 24 months: a meta-analysis. (2020)
Proportion 0.929 [0.889, 0.956]18 studiesUngraded
Intervention NR
Clinical and radiographic success · MTA vs CH, 3 months (El-Meligy 2006)
Materials for pulpotomy in immature permanent teeth: a systematic review and meta-analysis. (2019)
no estimate extracted1 studyUngraded
Intervention NR
Restorative index, primary teeth
Dental caries experience, care index and restorative index in children with learning disabilities and… (2019)
no estimate extracted2 studiesUngraded
Intervention NR
Dental calculus accumulation · -
Oral health in children and adolescents with juvenile idiopathic arthritis - a systematic review and… (2019)
Calculus index (presence) NR (significantly higher in JIA)1 studyUngraded
Intervention NR
Care index, primary teeth · Disability: autism
Dental caries experience, care index and restorative index in children with learning disabilities and… (2019)
no estimate extracted2 studiesUngraded
Intervention NR
Clinical and radiographic success · MTA vs CH, 18 and 24 months (Ozgur 2017)
Materials for pulpotomy in immature permanent teeth: a systematic review and meta-analysis. (2019)
no estimate extracted1 studyUngraded
Intervention NR
Overall failure
Pulpotomy versus pulpectomy in the treatment of vital pulp exposure in primary incisors. A systematic review… (2018)
no estimate extracted2 studiesUngraded
Intervention NR
Between-trial variance (fluoride caries NMR) · Random-effects NMR, independent interactions
Graphs of study contributions and covariate distributions for network meta-regression. (2018)
Posterior median between-trial variance 0.03 [0.02, 0.05]NRUngraded
Intervention NR
Caries and/or fillings in adjacent teeth · Occlusal surfaces (extraction vs FPM present; more decayed/filled with extraction)
Consequences of early extraction of compromised first permanent molar: a systematic review. (2018)
OR 1.64 [1.35, 2.1]1 studyUngraded
Intervention NR
Remineralisation of early enamel caries · NaF varnish plus chlorhexidine or calcium fluoride vs NaF varnish alone (no significant added benefit)
Caries remineralisation and arresting effect in children by professionally applied fluoride treatment - a… (2016)
no estimate extracted3 studiesUngraded
Intervention NR
Serum inflammatory cytokines (IL-1b, IL-6) and cortisol in periodontitis · Registered job/family stress
Social-Biological Interactions in Oral Disease: A 'Cells to Society' View. (2016)
Narrative (no effect size) No correlation between registered stress and serum IL-1b/IL-6/cortisol; untreated aggressive periodontitis showed pessimistic attitude and elevated serum IL-61 studyUngraded
Intervention NR
Development of carious lesions on sealed occlusal pits and fissures · 60 months
Caries-Preventive Effect of High-Viscosity Glass Ionomer and Resin-Based Fissure Sealants on Permanent… (2016)
RD -0.07 [-0.14, -0.01]2 studiesUngraded
Intervention NR
Enamel surface properties (thinner, softer enamel) in exfoliated teeth · By race/ethnicity
Social-Biological Interactions in Oral Disease: A 'Cells to Society' View. (2016)
Narrative (no effect size) Higher salivary cortisol reactivity associated with thinner, softer enamel surfaces1 studyUngraded
Intervention NR
Technical performance / deficient preparations (DHATs) · Composite preparations
Reducing Alaska Native paediatric oral health disparities: a systematic review of oral health interventions… (2013)
Deficient preparations (%) 02 studiesUngraded