Non-Cochrane · intervention · PM33023550

Does Er,Cr:YSGG reduce the microleakage of restorations when used for cavity preparation? A systematic review and meta-analysis.

Zhang Yali, Chen Wenfei, Zhang Jinrui, et al. · BMC oral health · 2020 · PubMed · doi:10.1186/s12903-020-01252-x

Oral HealthDental cariesAMSTAR 2: critically low (both extractors)
Full textEvery question was extracted from the full text, figures and supplements by two independent LLM extractors, disagreements adjudicated. Rows cite where in the review the value comes from.
Questions
10
current version
GRADE rated
0
No studies
0
Included studies
23
linked below
No studies 0 · 0%Ungraded 10 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Review question

ElementPlanned (methods)Found (results)
PopulationHuman teeth requiring cavity preparation and restoration; RCTs/quasi-RCTs; drop-out <20%Human extracted teeth in vitro (n=13 studies; primary teeth, premolars, third molars, posterior teeth)
InterventionEr,Cr:YSGG laser cavity preparation; prior acid etching after laser preparationEr,Cr:YSGG laser preparation (n=13); prior acid etching after laser preparation (n=4)
ComparisonTraditional bur cavity preparation; laser preparation without additional acid etchingTraditional bur preparation (n=13); laser without additional acid etching (n=4)
OutcomesMicroleakage of restorationsIncidence of microleakage by dye penetration (n=11 in meta-analysis; 2 summarized qualitatively)
Study designsRCTs or quasi-RCTsIn vitro RCTs/quasi-RCTs, parallel design (n=13)
TimingNot specifiedNot specified (in vitro)

Search date: July 2019. Databases: PubMed, EBSCO, Embase, Cochrane Controlled Register of Trials (CENTRAL)

Questions and results

Traditional bur cavity preparation vs Er,Cr:YSGG laser cavity preparation

Population: Human teeth requiring cavity preparation and restoration (in vitro)
4 questions
OutcomeEffectEvidenceStatus / GRADE
Incidence of microleakage
Dentin margin
At the dentin margin, microleakage did not differ significantly between bur and Er,Cr:YSGG laser preparation (RR 1.26, 95% CI 0.67-2.38; ungraded).
Source: Results, 'Primary outcomes' para; Fig. 3 · same question in other reviews
RR 1.26 [0.67, 2.38]6 studiesUngraded
Incidence of microleakage
Whole marginal line
Along the whole marginal line, microleakage did not differ significantly between bur and Er,Cr:YSGG laser preparation (RR 1.27, 95% CI 0.44-3.67; ungraded).
Source: Results, 'Primary outcomes' para; Fig. 3 · same question in other reviews
RR 1.27 [0.44, 3.67]5 studiesUngraded
Incidence of microleakage
Er,Cr:YSGG laser cavity preparation produced microleakage similar to traditional burs, with no significant difference (RR 1.03, 95% CI 0.85-1.25; ungraded).
Source: Results, 'Primary outcomes' para; Fig. 3 · same question in other reviews
RR 1.03 [0.85, 1.25]11 studiesUngraded
Incidence of microleakage
Enamel margin
At the enamel margin, microleakage did not differ significantly between bur and Er,Cr:YSGG laser preparation (RR 0.87, 95% CI 0.60-1.27; ungraded).
Source: Results, 'Primary outcomes' para; Fig. 3 · same question in other reviews
RR 0.87 [0.60, 1.27]6 studiesUngraded

No additional acid etching (self-etch adhesive alone) after Er,Cr:YSGG preparation vs Prior acid etching before self-etch adhesive after Er,Cr:YSGG preparation

Population: Er,Cr:YSGG laser-prepared cavities restored with self-etch adhesive systems (in vitro)
3 questions
OutcomeEffectEvidenceStatus / GRADE
Incidence of microleakage
Dentin margin
At the dentin margin, prior acid etching with self-etch adhesives significantly reduced microleakage (RR 2.44, 95% CI 1.38-4.34; ungraded).
Source: Results, 'Secondary outcomes' para; Fig. 4 · same question in other reviews
RR 2.44 [1.38, 4.34]2 studiesUngraded
Incidence of microleakage
Enamel margin
At the enamel margin, prior acid etching with self-etch adhesives significantly reduced microleakage (RR 3.0, 95% CI 1.54-5.83; ungraded).
Source: Results, 'Secondary outcomes' para; Fig. 4 · same question in other reviews
RR 3.00 [1.54, 5.83]2 studiesUngraded
Incidence of microleakage
Prior acid etching with self-etch adhesives significantly reduced microleakage after Er,Cr:YSGG preparation (RR 2.69 for no-etch vs etch, 95% CI 1.74-4.15; ungraded).
Source: Results, 'Secondary outcomes' para; Fig. 4 · same question in other reviews
RR 2.69 [1.74, 4.15]2 studiesUngraded

No additional acid etching (etch-and-rinse adhesive alone) after Er,Cr:YSGG preparation vs Prior acid etching before etch-and-rinse adhesive after Er,Cr:YSGG preparation

Population: Er,Cr:YSGG laser-prepared cavities restored with etch-and-rinse adhesive systems (in vitro)
1 question
OutcomeEffectEvidenceStatus / GRADE
Incidence of microleakage
Prior acid etching with etch-and-rinse adhesives did not significantly change microleakage after Er,Cr:YSGG preparation (RR 1.18, 95% CI 0.63-2.22; ungraded).
Source: Results, 'Secondary outcomes' para; Fig. 5 · same question in other reviews
RR 1.18 [0.63, 2.22]2 studiesUngraded

Comparison

2 questions
OutcomeEffectEvidenceStatus / GRADE
Microleakage/infiltration index: Er,Cr:YSGG vs traditional bur
Geraldo-Martins 2013 (excluded from meta-analysis; higher microleakage with Er,Cr:YSGG)
Qualitative NR [NR, NR]1 studyUngraded
Incidence of microleakage: Er,Cr:YSGG vs traditional bur (whole marginal line)
Rossi 2008 (excluded from meta-analysis; no significant difference)
Qualitative NR [NR, NR]1 studyUngraded

AMSTAR 2 appraisal

Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.

ItemExtractor AExtractor BAgree
1Research question includes PICO componentsYesYesyes
2Protocol established before the reviewcriticalNoNoyes
3Choice of study designs explainedNoNoyes
4Comprehensive literature searchcriticalPartial YesPartial Yesyes
5Study selection in duplicateYesYesyes
6Data extraction in duplicateYesYesyes
7List of excluded studies with reasonscriticalNoNoyes
8Included studies described in detailYesYesyes
9Risk of bias assessed satisfactorilycriticalRCT: Yes · NRSI: N/ANRSI: N/A · RCT: Yesno
10Funding of included studies reportedNoNoyes
11Appropriate meta-analysis methodscriticalRCT: Yes · NRSI: N/ANRSI: N/A · RCT: Yesno
12Impact of risk of bias on the pooled resultsNoNoyes
13Risk of bias accounted for in interpretationcriticalYesYesyes
14Heterogeneity explainedYesYesyes
15Publication bias investigatedcriticalNoNoyes
16Conflicts of interest reportedYesYesyes
OverallCritically LowCritically Lowyes

Included primary studies 23

Open as a trial list
StudyAlso included byOutcomes it informs hereTrial PICOResults
Ergin 2018
Comparison of Er,Cr:YSGG Laser Handpieces for Class II Preparation and Microleakage of Silorane- or Methacrylate-Based Composite…
DOI:10.1089/pho.2018.4459
this review onlyIncidence of microleakagenot extracted yetnot extracted yet
Ergin 2018
Comparison of Er,Cr:YSGG Laser Handpieces for Class II Preparation and Microleakage of Silorane- or Methacrylate-Based Composite…
PMID:30188252
this review onlynot statednot extracted yetnot extracted yet
Fattah 2013
Er,Cr:YSGG laser influence on microleakage of class V composite resin restorations
DOI:10.1007/s10103-012-1200-6
this review onlyIncidence of microleakagenot extracted yetnot extracted yet
Fattah 2013
Er,Cr:YSGG laser influence on microleakage of class V composite resin restorations.
PMID:23010956
this review onlynot statednot extracted yetnot extracted yet
Geraldo-Martins 2013
The Use of Bur and Laser for Root Caries Treatment: A Comparative Study
DOI:10.2341/11-345-l
this review onlyIncidence of microleakagenot extracted yetnot extracted yet
Geraldo-Martins 2013
The use of bur and laser for root caries treatment: a comparative study.
PMID:23088186
this review onlynot statednot extracted yetnot extracted yet
Gutknecht 2001
Microleakage of composite fillings in Er,Cr:YSGG laser‐prepared class II cavities
DOI:10.1002/lsm.1064
this review onlynot statednot extracted yetnot extracted yet
Gutknecht 2001
Microleakage of composite fillings in Er,Cr:YSGG laser-prepared class II cavities.
PMID:11344519
this review onlynot statednot extracted yetnot extracted yet
Malekafzali 2017
Comparison of marginal microleakage of flowable composite restorations in primary canine teeth prepared with high-speed diamond bur,…
PMID:29133967
this review onlyIncidence of microleakagenot extracted yetnot extracted yet
Marotti 2010
Influence of etching with erbium, chromium:yttrium–scandium–gallium–garnet laser on microleakage of class V restoration
DOI:10.1007/s10103-008-0623-6
this review onlyIncidence of microleakagenot extracted yetnot extracted yet
Marotti 2010
Influence of etching with erbium, chromium:yttrium-scandium-gallium-garnet laser on microleakage of class V restoration.
PMID:19011950
this review onlynot statednot extracted yetnot extracted yet
Rossi 2008
matched by author and year (probable)
this review onlyIncidence of microleakagenot extracted yetnot extracted yet
Rossi 2008
Microleakage of glass ionomer restoration in cavities prepared by Er,Cr:YSGG laser irradiation in primary teeth.
PMID:18647510
this review onlynot statednot extracted yetnot extracted yet
Shafiei 2014
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Shafiei 2014
Sealing of silorane-based composite in laser-prepared primary teeth: effect of acid etching.
PMID:25303503
this review onlynot statednot extracted yetnot extracted yet
Shafiei 2015
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Shafiei 2015
Effect of Acid Etching on Long-term Microleakage of Nano Ionomer Restorations in Burand Laser-prepared Cavities in Primary Teeth.
PMID:25909836
this review onlynot statednot extracted yetnot extracted yet
Shahabi 2008
Microleakage of composite resin restorations in cervical cavities prepared by Er,Cr:YSGG laser radiation
DOI:10.1111/j.1834-7819.2008.00028.x
this review onlynot statednot extracted yetnot extracted yet
Shahabi 2008
Microleakage of composite resin restorations in cervical cavities prepared by Er,Cr:YSGG laser radiation.
PMID:18494974
this review onlynot statednot extracted yetnot extracted yet
Subramaniam 2016
Assessment of Microleakage of a Composite Resin Restoration in Primary Teeth Following Class III Cavity Preparation Using Er, Cr: YSGG…
PMID:28144438
this review onlyIncidence of microleakagenot extracted yetnot extracted yet
Trelles 2012
Microleakage in Class V cavities with self-etching adhesive system and conventional rotatory or laser Er,Cr:YSGG.
PMID:24511195
this review onlyIncidence of microleakagenot extracted yetnot extracted yet
Yazici 2012
Comparison of the Er,Cr:YSGG laser with a chemical vapour deposition bur and conventional techniques for cavity preparation: a…
DOI:10.1007/s10103-010-0833-6
this review onlyIncidence of microleakagenot extracted yetnot extracted yet
Yazici 2012
Comparison of the Er,Cr:YSGG laser with a chemical vapour deposition bur and conventional techniques for cavity preparation: a…
PMID:20842517
this review onlynot statednot extracted yetnot extracted yet