Normalcy of diet (total parenteral nutrition) · Adults with cancer receiving treatment
Granulocyte-macrophage colony-stimulating factor (GM-CSF) showed no clear difference in normalcy of diet (total parenteral nutrition) compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Children with acute lymphoblastic leukaemia receiving chemotherapy alone
Keratinocyte growth factor (KGF), intravenous led to lower oral mucositis (severe) compared with chlorhexidine mouthwash; GRADE not reported.
1 finding from 1 review
Swelling (mean) · Adults (>16 years old) undergoing orthognathic surgery
1 finding from 1 review
Resorbable versus titanium plates for orthognathic surgery 2017 · Cochrane All outcomesUp to 3 years postoperatively
Though Cheung 2004 reported the presence of postoperative swelling, it was only noted in conjunction with infection and pus discharge; assessment of this outcome did not include the use of photography or digital…
1 study · 60 participants
GRADE not reported
Number of days of treatment with opioid analgesics · Adults with cancer receiving treatment
Granulocyte-macrophage colony-stimulating factor (GM-CSF) led to lower number of days of treatment with opioid analgesics compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Xerostomia (grade >= 2, 0-4 scale) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
Amifostine 200 mg/m2 three times weekly showed no clear difference in xerostomia (grade >= 2, 0-4 scale) compared with amifostine 200 mg/m2 five times weekly; GRADE not reported.
1 finding from 1 review
Taste acuity improvement - objective outcome (dichotomous) - chronic renal failure · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
Zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… led to higher taste acuity improvement - objective outcome (dichotomous) - chronic… compared with placebo; GRADE not reported.
1 finding from 1 review
Bridge complications · Adults (18 years or older) needing a three-unit fixed dental prosthesis (FDP)
It is very uncertain whether metal-free FDPs (zirconia ceramic) changes bridge complications compared with metal-ceramic FDPs (very low certainty).
1 finding from 1 review
Mouth and throat soreness (OMWQ-HN, 0-4 scale) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
Palifermin showed no clear difference in mouth and throat soreness (OMWQ-HN, 0-4 scale) compared with placebo; GRADE not reported.
1 finding from 1 review
MD -0.12 [-0.27, 0.02]
2 studies
GRADE not reported
Oral mucositis (any severity) · Adults receiving chemotherapy alone for colorectal cancer
1 finding from 1 review
Success of surgery (eruption of the canine crown sufficient for orthodontic alignment, without repeated surgery) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)
Open surgical exposure showed no clear difference in success of surgery (eruption of the canine crown sufficient for… compared with closed surgical exposure (low certainty).
1 finding from 1 review
Dry mouth (xerostomia) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
1 finding from 1 review
Probing pocket depth · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
Periodontal treatment (scaling and root planing, alone or with… led to lower probing depth compared with alternative (less intensive) periodontal treatment, alone or with…; GRADE not reported.
1 finding from 1 review
Treatment time: length of time in the operating theatre (first incision to final suture) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)
It is very uncertain whether open surgical exposure changes treatment time: length of time in the operating theatre (first… compared with closed surgical exposure (very low certainty).
1 finding from 1 review
Taste acuity improvement - objective outcome (continuous data) · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes taste acuity improvement - objective outcome (continuous data) compared with placebo (very low certainty).
1 finding from 1 review
Oral mucositis (moderate to severe) · Adults with cancer receiving treatment
It is very uncertain whether granulocyte-colony stimulating factor (G-CSF) changes oral mucositis (moderate to severe) compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Gum health: radiographic crestal bone level · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)
Open surgical exposure showed no clear difference in gum health: radiographic crestal bone level compared with closed surgical exposure; GRADE not reported.
1 finding from 1 review
Patient satisfaction (measured by patient satisfaction or aesthetic scales) · Adults (18 years or older) needing a three-unit fixed dental prosthesis (FDP)
It is very uncertain whether metal-free FDPs (zirconia ceramic) changes aesthetic evaluation (patient aesthetic satisfaction changes) compared with metal-ceramic FDPs (very low certainty).
1 finding from 1 review
Interruptions to cancer treatment (radiotherapy breaks longer than two days) · Adults with cancer receiving treatment
Epidermal growth factor (EGF), oral spray showed no clear difference in interruptions to cancer treatment (radiotherapy breaks longer than… compared with placebo; GRADE not reported.
1 finding from 1 review
Failure to complete orthodontic treatment due to pain · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review
Small‐for‐gestational age · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
The review found no eligible studies for this question.
1 finding from 1 review