Findings

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Evidence found and GRADE certainty

3,032 questions · 3,358 findings · 190 reviews · Oral Health · related questions CL0289

No studies found 599 · 17.8%GRADE not reported 1,759 · 52.4%Very low 612 · 18.2%Low 269 · 8%Moderate 107 · 3.2%High 12 · 0.4%

Baby-led weaning (BLW) / BLISS vs Traditional complementary feeding (TCF)

Choking · Healthy children aged 6–24 months in Western industrialized countries

No statistically significant difference in choking events between BLW/BLISS and TCF was reported.

1 finding from 1 review

Hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy vs conventional therapy

Healing of MRONJ · People with established (manifest) MRONJ

It is very uncertain whether hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy changes healing of MRONJ compared with conventional therapy (very low certainty).

1 finding from 1 review

CBT plus hypnosis (combined package) vs usual care

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer

CBT plus hypnosis (combined package) led to lower pain intensity compared with usual care; GRADE not reported.

1 finding from 1 review

Traditional screening (referral card given if the inspecting dentist judges the child needs to see a dentist) vs No screening

Malocclusion or orthodontic treatment needs measured by any validated index · School children (aged 4 to 15 years), primary and secondary schools in the UK and India

The review found no eligible studies for this question.

1 finding from 1 review

Baby-Led Introduction to SolidS (BLISS) vs Traditional complementary feeding (TCF)

Overweight/obesity risk · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western industrialized countries

In RCTs, BLISS did not significantly change overweight/obesity risk versus traditional feeding (RR 0.15, 95% CI 0.00 to 17.79; low certainty).

1 finding from 1 review

Traditional screening (referral card given if the inspecting dentist judges the child needs to see a dentist) vs No screening

Proportion of children with other untreated oral health needs · School children (aged 4 to 15 years), primary and secondary schools in the UK and India

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis before dental procedure vs placebo or no prophylaxis

Development of endocarditis due to other (non-dental) causes · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure

The review found no eligible studies for this question.

1 finding from 1 review

Dental examinations at three-month intervals and preventive treatments vs usual care

MRONJ (incidence proportion) · Men with metastatic prostate cancer receiving intravenous zoledronic acid (at risk of MRONJ)

It is very uncertain whether dental examinations at three-month intervals and preventive treatments changes MRONJ (incidence proportion) compared with standard care (very low certainty).

1 finding from 1 review

Metronidazole gel 25% (local antibiotic) vs Placebo gel

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

Metronidazole gel (25%, intrasocket) showed no clear difference in presence of dry socket compared with placebo gel; GRADE not reported.

1 finding from 1 review

Non-responsive complementary feeding (NRCF) vs Other models of complementary feeding

Overweight/obesity risk · Healthy children aged 6–24 months in Western industrialized countries

NRCF showed no significant association with overweight/obesity across the reported comparisons (very low certainty).

1 finding from 1 review

Referral to a specific dental treatment facility vs Generic advice letter to see a dentist

Number of caries in primary teeth (dt index) · School children, primary school in Saudi Arabia

It is very uncertain whether referral to a specific dental treatment facility changes number of caries in primary teeth (dt index) compared with generic advice letter to see a dentist (very low certainty).

1 finding from 1 review

Amoxicillin + metronidazole + SRP vs Supragingival scaling (plus placebo)

All‐cause death · People with periodontitis and metabolic syndrome (no CVD; primary prevention)

It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes all-cause death compared with supragingival scaling (plus placebo) (very low certainty).

1 finding from 1 review

Autologous platelet‐rich plasma vs placebo or no treatment

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

It is very uncertain whether platelet rich plasma changes presence of dry socket compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Single-visit root canal treatment vs Multiple-visit root canal treatment (two or more visits)

Pain at 12 months or more (long-term postobturation pain) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
1 finding from 1 review

Artemisia desertorum spreng (Yunnan) vs placebo

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

Artemisia desertorum spreng (Yunnan) showed no clear difference in presence of dry socket compared with placebo; GRADE not reported.

1 finding from 1 review