Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,032 questions · 3,358 findings · 190 reviews · Oral Health · related questions CL0289

No studies found 599 · 17.8%GRADE not reported 1,759 · 52.4%Very low 612 · 18.2%Low 269 · 8%Moderate 107 · 3.2%High 12 · 0.4%

Hyperbaric oxygen vs No HBO therapy

Postimplantation complications · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

Hyperbaric oxygen (HBO) therapy showed no clear difference in postimplantation complications compared with no HBO therapy; GRADE not reported.

1 finding from 1 review

Locking plate vs 2 mm non-locking titanium plates

Restoration of function (functional occlusion; bite force as surrogate) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Functional occlusion was achieved in all participants in both intervention groups (Agarwal 2011); the measurement of this outcome was not clearly reported. Bite force was reported as a surrogate/proxy outcome.
    1 study
    GRADE not reported

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Implant failure · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) probably leads to lower implant failure compared with no antibiotics or placebo (moderate certainty).

1 finding from 1 review

One microplate plus one miniplate vs Two miniplates

Efficacy and stability of fixation (bite force) · Adults with isolated mandibular fractures in the interforaminal region
1 finding from 1 review
  • Only one study (Gupta 2012) compared one microplate in conjunction with one miniplate versus two miniplates in isolated interforaminal fractures; however, the data reported in the trial did not satisfy the review's…
    1 study
    GRADE not reported

Fixation (splinting) vs No splint, or a different type or duration of splint

Outcome not reported · Patients (mainly children and young adults) with a history of dental trauma and a diagnosis of luxation (intrusion, extrusion, or lateral…

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Assessment of the alignment of the lower front teeth using any method or index · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Self etching primer (one-step etchant-and-primer technique) vs Conventional etchants (two-step etch and prime method using 37% phosphoric acid)

Decay (decalcification) associated with or around the etching field · Children and adults with fixed orthodontic brackets bonded to incisors, canines and premolars
1 finding from 1 review
  • Decay (decalcification) associated with or around the etching field: Only one study (Ghiz 2009) assessed this outcome but data were reported at the tooth level rather than at the participant level and therefore was not…
    1 study · 25 participants
    GRADE not reported

Extraction of the primary maxillary canine vs no intervention

Time to eruption of the permanent canine · Children with palatally displaced maxillary canines (at least 80% aged 10 to 13 years); trials with craniofacial syndromes or anomalies…
1 finding from 1 review

Implant surface smoothening added to systemic antibiotics + resective surgery + local antibiotics vs No implant surface smoothening (same surgical protocol)

Implant failure · People with at least one dental implant affected by perimplantitis

Implant surface smoothening added to systemic antibiotics +… showed no clear difference in implant failure compared with no implant surface smoothening (same surgical protocol); GRADE not reported.

1 finding from 1 review

Radix tripterygium hypoglaucum tablet (THT) vs Tripterygium glucosides tablet (TGT)

Partial response (remarkably effective or effective) · People with erosive oral lichen planus

Radix tripterygium hypoglaucum tablet (THT) led to lower partial response (remarkably effective or effective) compared with tripterygium glucosides tablet (TGT); GRADE not reported.

2 findings from 1 review

Topical clobetasol propionate 0.025% vs clobetasol cream 0.05% cream

Physician Global Assessment (Thongprasom score) · People with erosive oral lichen planus

Topical clobetasol propionate 0.025% showed no clear difference in physician Global Assessment (Thongprasom score) compared with topical clobetasol propionate 0.05%; GRADE not reported.

1 finding from 1 review

Non-surgical interventions vs Surgical interventions

Outcome not reported · People with at least one dental implant affected by peri-implantitis

The review found no eligible studies for this question.

1 finding from 1 review

Sodium hypochlorite (NaOCl), 2.5% to 5.25% vs Sodium hypochlorite 1%

Change in periapical radiolucency (radiography or CBCT), up to 1 year after treatment · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…

The review found no eligible studies for this question.

1 finding from 1 review