Cochrane · intervention · CD003603
Interventions for replacing missing teeth: hyperbaric oxygen therapy for irradiated patients who require dental implants
Esposito, M, Worthington, HV · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
Full textEvery question was extracted from the full review (methods and results), not only its Summary of Findings table.
Questions
7
current version
GRADE rated
1
No studies
1
Included studies
1
as reported
No studies 1 · 14.3%Ungraded 5 · 71.4%Very low 1 · 14.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants | 26 patients included (13 HBO therapy, 13 no HBO therapy); 2 patients died during healing period (1 from each group); 3 additional patients in each group died one year after overdenture placement |
| Intervention | Hyperbaric oxygen (HBO) therapy | HBO therapy (n=13) |
| Comparison | No HBO therapy | No HBO therapy (n=13) |
| Outcomes | Prosthesis failure if secondary to implant failure; Implant failure: mobility and removal of stable implants dictated by progressive marginal bone loss; Radiographic marginal bone level changes on intraoral radiographs taken with a parallel technique; Preimplantation complications (eustachian tube dysfunction, tympanic membrane rupture, ear or sinus or tooth pain, pneumothorax, etc.); Postimplantation complications (mucosa ulceration, osteoradionecrosis, etc.); Patient satisfaction; Cost effectiveness | Prosthetic failures (n=24); Implant failures (n=24); Preimplantation complications (n=24); Postimplantation complications (n=24); Overall denture satisfaction (n=17) |
| Study designs | Randomised controlled trials | Randomised controlled trial (n=1) |
| Timing | Not specified | One year after delivery of the prosthesis |
Search date: 2013-06. Databases: Cochrane Oral Health's Trials Register; Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE; EMBASE
Questions and results
Show all 3 versionsHyperbaric oxygen (HBO) therapy vs No HBO therapy
Population: Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Preimplantation complications | Analysis 1.1 (Dichotomous outcomes: Preimplantation complications): Risk Ratio (M-H, Fixed, 95% CI), totals not selected; not estimable (no events in either arm). | 1 study · 24 participants | Ungraded |
Radiographic marginal bone level changes | Radiographic bone level changes (but not used since extrapolated from oblique lateral radiographs). | 1 study | Ungraded |
Prosthetic failure 1 year after delivery of the prosthesis | RR 3.00 [0.13, 67.06] Without HBO: low-risk population 10 per 1000; high-risk population 100 per 1000 vs With HBO: low-risk population 30… | 1 study · 24 participants | Very low Downgraded: risk of bias, imprecision |
Patient satisfaction (overall denture satisfaction) 1 year after delivery of the prosthesis | Analysis 1.2 (Overall denture satisfaction): Mean Difference (IV, Fixed, 95% CI), totals not selected (value not displayed). | 1 study · 17 participants | Ungraded |
Cost effectiveness | Cost effectiveness data were not presented but it was possible to extrapolate this. | 0 studies | No studies |
Implant failure 1 year after delivery of the prosthesis | RR 2.5 [0.60, 10.46] | 1 study · 24 participants | Ungraded |
Postimplantation complications 1 year after delivery of the prosthesis | RR 5.0 [0.27, 94.34] | 1 study · 24 participants | Ungraded |