Findings

What do systematic reviews say?

3,032 questions · 3,358 findings · 190 reviews · related questions CL0289

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No studies found 599 · 17.8%GRADE not reported 1,759 · 52.4%Very low 612 · 18.2%Low 269 · 8%Moderate 107 · 3.2%High 12 · 0.4%

Transbond Plus self etching primer (3M Unitek) vs Clearfil Protect Bond self etching primer (Kuraray Medical)

Decay (decalcification) associated with or around the etching field · Children and adults with fixed orthodontic brackets bonded to incisors, canines and premolars

1 finding from 1 review

Enamel etching for bonding fixed orthodontic braces 2013 · Cochrane All outcomes
Decalcification outcomes in Paschos 2009 were reported at tooth level rather than at participant level; the evidence was insufficient to conclude whether or not there is a difference in decalcification between the…
1 study
GRADE not reported

Electrostimulation (device) vs Placebo (sham/placebo device)

Stimulated whole saliva (SWS) · Adults with dry mouth due to Sjogren's Syndrome

It is very uncertain whether electrostimulation (device) changes stimulated whole saliva (SWS) compared with placebo (sham/placebo device) (very low certainty).

1 finding from 1 review

Interventions for the management of dry mouth: non‐pharmacological interventions 2013 · Cochrane All outcomes
End of treatment (4 weeks)
MD 0.16 [-0.05, 0.37]
1 study · 24 participants
Very low

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Delay in start of radiation treatment · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…

The review found no eligible studies for this question.

1 finding from 1 review

Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Acupuncture vs sham

Stimulated whole saliva (SWS) · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome

Acupuncture may leads to higher stimulated whole saliva (SWS) compared with placebo (sham acupuncture) (low certainty).

2 findings from 1 review

Interventions for the management of dry mouth: non‐pharmacological interventions 2013 · Cochrane All outcomes
12 months (1 year follow-up)
MD 0.28 [0.09, 0.47]
2 studies · 54 participants
Low
Interventions for the management of dry mouth: non‐pharmacological interventions 2013 · Cochrane All outcomes
End of treatment (4-6 weeks)
MD 0.19 [0.07, 0.31]
3 studies · 71 participants
Low

Transbuccal miniplate combined with intraoral approach vs Intraoral approach alone

Post-operative infection (persistent) · Adults with fractures of the mandibular angle

Transbuccal miniplate combined with intraoral approach showed no clear difference in post-operative infection (persistent) compared with intraoral approach alone; GRADE not reported.

1 finding from 1 review

Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
3 months · Angle of mandible only
RR 0.47 [0.20, 1.09]
1 study · 138 participants
GRADE not reported

Early loading vs Conventional loading

Implant failure · Patients who are having osseointegrated root-form dental implants

Early loading showed no clear difference in implant failure compared with conventional loading; GRADE not reported.

1 finding from 1 review

Interventions for replacing missing teeth: different times for loading dental implants 2013 · Cochrane All outcomes
1 year
RR 1.55 [0.46, 5.18]
2 studies
GRADE not reported

Intraoral distalising appliance vs Another (different) intraoral distalising appliance

Duration of treatment · Children and adolescents (aged 16 years or less at the start of treatment) undergoing orthodontic treatment to distalise upper first…

1 finding from 1 review

Orthodontic treatment for distalising upper first molars in children and adolescents 2013 · Cochrane All outcomes
Duration of treatment reported by 2 studies (Altug-Atac 2008, Karacay 2006); not GRADE-rated and not in a SoF table. 3D bimetric distalising arch 3.4 months vs modified Begg intraoral distalising system 6.5 months (MD…
2 studies
GRADE not reported

One prophylactic antibiotic vs A different prophylactic antibiotic

Outcome not reported · Adults undergoing dental implant placement

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications 2013 · Cochrane All outcomes
At least 3 months (planned)
no estimate extracted
0 studies
No studies found

Occlusal loading vs Non-occlusal loading

Prosthesis failure · Patients who are having osseointegrated root-form dental implants

Occlusal loading showed no clear difference in prosthesis failure compared with non-occlusal loading; GRADE not reported.

1 finding from 1 review

Interventions for replacing missing teeth: different times for loading dental implants 2013 · Cochrane All outcomes
1 year
RR 1.00 [0.31, 3.22]
2 studies
GRADE not reported

Transbond Plus self etching primer (3M Unitek) vs First Step self etching primer (Reliance Orthodontic Products)

Bond failure rate · Children and adults with fixed orthodontic brackets bonded to incisors, canines and premolars

1 finding from 1 review

Enamel etching for bonding fixed orthodontic braces 2013 · Cochrane All outcomes
Noble 2006 (split-mouth) compared Transbond Plus versus First Step SEP; the bond failure rate was reported at tooth level rather than at participant level and was not amenable to analysis; the evidence was insufficient…
1 study
GRADE not reported

Immediate loading vs Conventional loading

Prosthesis failure · Patients who are having osseointegrated root-form dental implants

It is very uncertain whether immediate loading changes prosthesis failure compared with conventional loading (very low certainty).

1 finding from 1 review

Interventions for replacing missing teeth: different times for loading dental implants 2013 · Cochrane All outcomes
1 year
RR 1.90 [0.67, 5.34]
8 studies · 381 participants
Very low

Capitation remuneration vs Fee-for-service remuneration

Unintended effects: self-reported temptation to over-prescribe (0- to 100-point visual analogue scale) · Children (0- to 15-year-olds) undergoing routine continuing dental care at 354 dental practices, in matched pairs of Health Service…

Capitation remuneration showed no clear difference in unintended effects: self-reported temptation to over-prescribe (0-… compared with fee-for-service remuneration; GRADE not reported.

1 finding from 1 review

The effect of different methods of remuneration on the behaviour of primary care dentists 2013 · Cochrane All outcomes
3 years
MD -14.9
1 study
GRADE not reported

Electrostimulation (device) vs Placebo (sham/placebo device)

Patient satisfaction with treatment · Adults with dry mouth due to Sjogren's Syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the management of dry mouth: non‐pharmacological interventions 2013 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Two miniplates (transbuccal approach) vs One miniplate plus two screws (intraoral approach at external oblique ridge)

Requirement for additional (surgical) interventions (plate removal) · Adults with fractures of the mandibular angle

Two miniplates (transbuccal approach) showed no clear difference in requirement for additional (surgical) interventions (plate removal) compared with one miniplate plus two screws (intraoral approach at external…; GRADE not reported.

1 finding from 1 review

Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
Angle of mandible only
RR 0.78 [0.19, 3.11]
2 studies
GRADE not reported

Antibiotics (systemic) vs No antibiotics, placebo, or a different type of antibiotic

Outcome not reported · Patients (mainly children and young adults) with a history of dental trauma and a diagnosis of luxation (intrusion, extrusion, or lateral…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating traumatised permanent front teeth: luxated (dislodged) teeth 2013 · Cochrane All outcomes
Minimum 12 months follow-up
Types of antibiotics: the effect of using no antibiotics, a placebo or different types of antibiotics. Main results: No randomised or quasi-randomised controlled trials were found; no study was included in this review.
0 studies
No studies found

2 mm titanium plates vs 2.5 mm bioresorbable plates

Post-operative neurosensory disturbance (mental nerve paraesthesia) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

2 mm titanium plates led to higher post-operative neurosensory disturbance (mental nerve paraesthesia) compared with 2.5 mm bioresorbable plates; GRADE not reported.

1 finding from 1 review

Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
1 month
RR 1.77 [1.09, 2.88]
1 study · 57 participants
GRADE not reported

2 mm titanium plates vs 2.5 mm bioresorbable plates

Malocclusion · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

2 mm titanium plates showed no clear difference in malocclusion compared with 2.5 mm bioresorbable plates; GRADE not reported.

1 finding from 1 review

Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
1 month
RR 1.1 [0.32, 3.82]
1 study · 40 participants
GRADE not reported

Transbuccal miniplate combined with intraoral approach vs Intraoral approach alone

Facial appearance (scar) · Adults with fractures of the mandibular angle

1 finding from 1 review

Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
Angle of mandible only
The investigators reported that no patients were "recorded as having an unsatisfactory scar", but it was unclear how, when and by whom the assessments were made.
1 study
GRADE not reported

Two miniplates (transbuccal approach) vs One miniplate plus two screws (intraoral approach at external oblique ridge)

Facial appearance (scar) · Adults with fractures of the mandibular angle

1 finding from 1 review

Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
Angle of mandible only
Facial scarring, as a result of access through the transbuccal route, occurred in two participants in the two-miniplate group (Siddiqui 2007).
1 study
GRADE not reported

2 mm titanium plates vs 2.5 mm bioresorbable plates

Requirement for additional (surgical) interventions (plate removal / re-operation) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

1 finding from 1 review

Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
Plate removal was statistically more likely in the titanium group (Fisher's exact P<0.05); infection led to plate removal in one titanium participant at 2 months and a further 4/21 (19%) titanium participants (six…
1 study
GRADE not reported