What do systematic reviews say?

Partial caries removal (single stage; residual dentinal caries sealed into the tooth definitively) vs Complete caries removal

It is very uncertain whether partial caries removal (single stage; residual dentinal caries… changes failure of restorations compared with complete caries removal (very low certainty).

• Operative caries management in adults and children 2013 · Cochrane All outcomes

  1 year
  RR 0.33 [0.01, 7.62]
  1 study · 32 participants
  Very low

Transbuccal miniplate combined with intraoral approach vs Intraoral approach alone

Transbuccal miniplate combined with intraoral approach led to lower requirement for additional (surgical) interventions (plate removal… compared with intraoral approach alone; GRADE not reported.

• Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes

  90 days · Angle of mandible only
  RR 0.57 [0.33, 0.98]
  1 study · 140 participants
  GRADE not reported

Transbond Plus self etching primer (3M Unitek) vs Clearfil Protect Bond self etching primer (Kuraray Medical)

• Enamel etching for bonding fixed orthodontic braces 2013 · Cochrane All outcomes
  Self etching primers versus self etching primers: Two split-mouth studies compared two different SEPs (Noble 2006; Paschos 2009). The failure rates were reported at tooth level rather than at participant level. We…
  1 study
  GRADE not reported

Electrostimulation (device) vs Placebo (sham/placebo device)

• Interventions for the management of dry mouth: non‐pharmacological interventions 2013 · Cochrane All outcomes
  Neither trial reported usable dry mouth data; Talal 1992: 'patients using the active device experienced relief from six of the most common symptoms of xerostomia secondary to Sjogren's Syndrome, with two of these…
  Studies not reported
  GRADE not reported

Capitation remuneration vs Fee-for-service remuneration

Capitation remuneration led to lower measures of non-clinical behaviour: proportion of dentists… compared with fee-for-service remuneration; GRADE not reported.

• The effect of different methods of remuneration on the behaviour of primary care dentists 2013 · Cochrane All outcomes

  3 years
  RR 0.81
  1 study
  GRADE not reported

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

The review found no eligible studies for this question.

• Interventions for managing relapse of the lower front teeth after orthodontic treatment 2013 · Cochrane All outcomes
  No RCTs met the inclusion criteria for this review. After deduplication, the electronic searching identified 527 publications; after reviewing the titles and abstracts, none focused on interventions to correct the…
  0 studies
  No studies found

Zygomatic implants with bone grafts (as a partial alternative to bone augmentation; some augmentation still required in the frontal maxilla) vs Conventional dental implants in augmented maxillae

The review found no eligible studies for this question.

• Interventions for replacing missing teeth: dental implants in zygomatic bone for the rehabilitation of the severely… 2013 · Cochrane All outcomes

  At least 1 year in function
  Results (Effects of interventions): we could not identify any eligible randomised controlled trials (RCTs).
  0 studies
  No studies found

Zygomatic implants without bone grafts (as a complete alternative to any bone augmentation procedure) vs Conventional dental implants in augmented maxillae

The review found no eligible studies for this question.

• Interventions for replacing missing teeth: dental implants in zygomatic bone for the rehabilitation of the severely… 2013 · Cochrane All outcomes

  At least 1 year in function
  Results (Effects of interventions): we could not identify any eligible randomised controlled trials (RCTs).
  0 studies
  No studies found

Visual screening (oral visual inspection) by trained health workers vs No screening

Visual screening (oral visual inspection) by trained health workers showed no clear difference in oral cancer mortality (disease-specific) compared with no screening (low certainty).

• Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes

  15-year follow-up
  RR 0.88 [0.69, 1.12]
  1 study · 191873 participants
  Low
• Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes

  15-year follow-up · High-risk individuals (tobacco and/or alcohol users)
  RR 0.76 [0.60, 0.97]
  1 study
  GRADE not reported

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Hyperbaric oxygen vs No HBO therapy

Hyperbaric oxygen (HBO) therapy led to lower preimplantation complications compared with no HBO therapy; GRADE not reported.

• Interventions for replacing missing teeth: hyperbaric oxygen therapy for irradiated patients who require dental implants 2013 · Cochrane All outcomes
  Analysis 1.1 (Dichotomous outcomes: Preimplantation complications): Risk Ratio (M-H, Fixed, 95% CI), totals not selected; not estimable (no events in either arm).
  1 study · 24 participants
  GRADE not reported

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Acupuncture vs sham

The review found no eligible studies for this question.

• Interventions for the management of dry mouth: non‐pharmacological interventions 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Two lag screws vs One lag screw (with arch bars and IMF)

• Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
  Restoration of the original occlusion, assessed visually, was similar in both groups (P>0.05); occlusal correction was not achieved in one participant in the two-lag-screws group. Surrogate/proxy outcome.
  1 study
  GRADE not reported

Combined paracetamol plus ibuprofen in a single tablet (e.g. paracetamol 1000 mg/ibuprofen 400 mg or 500/200 mg) vs Single drugs given separately (paracetamol 1000 mg or ibuprofen 400 mg)

Combined paracetamol plus ibuprofen in a single tablet (e.g.… showed no clear difference in proportion of patients with >50% maximum pain relief (TOTPAR) over 2… compared with single drugs given separately (paracetamol 1000 mg or ibuprofen 400… (moderate certainty).

• Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth 2013 · Cochrane All outcomes

  2 hours postdosing · Paracetamol 1000 mg/ibuprofen 400 mg vs paracetamol 1000 mg or ibuprofen 400 mg
  RR 1.29 [0.91, 1.85]
  1 study · 170 participants
  Moderate

Zygomatic implants without bone grafts (as a complete alternative to any bone augmentation procedure) vs Conventional dental implants in augmented maxillae

The review found no eligible studies for this question.

• Interventions for replacing missing teeth: dental implants in zygomatic bone for the rehabilitation of the severely… 2013 · Cochrane All outcomes

  At least 1 year in function
  Summary of findings 'Zygomatic implants versus conventional implants'; Prosthesis failure: Assumed risk (conventional) Low risk population 10 per 1000, High risk population 100 per 1000; Corresponding risk (zygomatic)…
  0 studies
  No studies found

Transbuccal miniplate combined with intraoral approach vs Intraoral approach alone

Transbuccal miniplate combined with intraoral approach showed no clear difference in non-union compared with intraoral approach alone; GRADE not reported.

• Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes

  Angle of mandible only
  RR 1.0 [0.17, 5.79]
  1 study · 140 participants
  GRADE not reported

Acupuncture vs sham

The review found no eligible studies for this question.

• Interventions for the management of dry mouth: non‐pharmacological interventions 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

3-dimensional (3D) miniplates vs Standard (Champy) plates

3-dimensional (3D) miniplates led to lower requirement for additional (surgical) interventions (post-operative… compared with standard (Champy) plates; GRADE not reported.

• Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
  RR 0.47 [0.25, 0.88]
  1 study · 50 participants
  GRADE not reported

Electrostimulation (device) vs Placebo (sham/placebo device)

The review found no eligible studies for this question.

• Interventions for the management of dry mouth: non‐pharmacological interventions 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found