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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
239 questions in 37 reviews · cluster CL0069
current versionsNo studies 4 · 1.7%Ungraded 170 · 71.1%Very low 42 · 17.6%Low 6 · 2.5%Moderate 10 · 4.2%High 7 · 2.9%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Early childhood caries (ECC) vs ECC-free children (caries-free controls) Serum ferritin level · Preschool children (<6 years) · Overall Iron deficiency and early childhood caries: a systematic review and meta-analysis. (2021) | WMD -5.80 [-11.97, 0.37] | 5 studies · 832 participants | Ungraded |
Observed population vs Not applicable Enamel dissolution prevalence · Five-year-old preschool children in Sharjah · Overall Oral Health of Children and Adolescents in the United Arab Emirates: A Systematic Review of the Past Decade. (2021) | Prevalence 55.0 | 1 study · 403 participants | Ungraded |
Observed population vs Not applicable Exposed dentin prevalence · Five-year-old preschool children in Sharjah · Overall Oral Health of Children and Adolescents in the United Arab Emirates: A Systematic Review of the Past Decade. (2021) | Prevalence 3.7 | 1 study · 403 participants | Ungraded |
Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls) Number of teeth · Adults (general and hospital populations assessed in case-control studies) Oral manifestations of patients with systemic sclerosis: a meta-analysis for case-controlled studies. (2021) | SMD -0.947 [-2.131, 0.237] | 3 studies | Ungraded |
0-19 remaining teeth vs 20-32 remaining teeth Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Adjusted for age/sex Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of… (2021) | HR 1.29 [1.08, 1.53] | 3 studies · 186749 participants | Ungraded |
0-19 remaining teeth vs 20-32 remaining teeth All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Adjusted for age/sex Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of… (2021) | HR 1.42 [1.15, 1.75] | 5 studies · 212657 participants | Ungraded |
Observed population vs Not applicable Dental information from educational programs · Mothers of preschool children in Sharjah · Overall Oral Health of Children and Adolescents in the United Arab Emirates: A Systematic Review of the Past Decade. (2021) | Prevalence 13 | 1 study | Ungraded |
Observed population vs Not applicable Tooth wear prevalence · School children aged 2.6-6.8 years in Abu Dhabi · Overall Oral Health of Children and Adolescents in the United Arab Emirates: A Systematic Review of the Past Decade. (2021) | Prevalence 97.6 | 1 study · 506 participants | Ungraded |
Edentulous (0 remaining teeth) vs 20-32 remaining teeth All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of… (2021) | RR 2.27 [1.82, 2.83] | 8 studies · 180222 participants | High |
Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls) Number of missing teeth · Adults (general and hospital populations assessed in case-control studies) Oral manifestations of patients with systemic sclerosis: a meta-analysis for case-controlled studies. (2021) | SMD 0.546 [-0.148, 1.241] | 4 studies | Ungraded |
Early childhood caries (ECC) vs ECC-free children (caries-free controls) Mean corpuscular volume (MCV) level · Preschool children (<6 years) · Overall Iron deficiency and early childhood caries: a systematic review and meta-analysis. (2021) | WMD -3.72 [-6.65, -0.79] | 5 studies · 924 participants | Ungraded |
Early childhood caries (ECC) vs ECC-free children (caries-free controls) Iron deficiency (ID) · Preschool children (<6 years) · Overall Iron deficiency and early childhood caries: a systematic review and meta-analysis. (2021) | OR 2.63 [1.85, 3.73] | 8 studies · 9151 participants | Ungraded |
Caries experience vs No caries experience Dental erosion · Five-year-old preschool children in Sharjah · Overall Oral Health of Children and Adolescents in the United Arab Emirates: A Systematic Review of the Past Decade. (2021) | OR 0.28 [0.16, 0.51] | 1 study · 403 participants | Ungraded |
Observed population vs Not applicable Dental information from relatives · Mothers of preschool children in Sharjah · Overall Oral Health of Children and Adolescents in the United Arab Emirates: A Systematic Review of the Past Decade. (2021) | Prevalence 27 | 1 study | Ungraded |
Observed population vs Not applicable Tooth brushing less than once daily, females in 2016 · Nationally surveyed adolescents in the United Arab Emirates · Overall Oral Health of Children and Adolescents in the United Arab Emirates: A Systematic Review of the Past Decade. (2021) | Prevalence 28.3 | 1 study · 24220 participants | Ungraded |
Observed population vs Not applicable Molar-incisor hypomineralization prevalence · School children in Dubai governmental schools · Overall Oral Health of Children and Adolescents in the United Arab Emirates: A Systematic Review of the Past Decade. (2021) | Prevalence 7.59 | 1 study · 779 participants | Ungraded |
0-19 remaining teeth vs 20-32 remaining teeth Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of… (2021) | RR 1.98 [1.86, 2.10] | 4 studies · 191129 participants | Moderate |
0-19 remaining teeth vs 20-32 remaining teeth Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Multivariable-adjusted Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of… (2021) | HR 1.19 [1.13, 1.26] | 4 studies · 191129 participants | Moderate |
Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls) Attachment loss (AL) · Adults (general and hospital populations assessed in case-control studies) Oral manifestations of patients with systemic sclerosis: a meta-analysis for case-controlled studies. (2021) | SMD 2.584 [0.321, 4.846] | 4 studies | Ungraded |
Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls) Number of filled teeth · Adults (general and hospital populations assessed in case-control studies) Oral manifestations of patients with systemic sclerosis: a meta-analysis for case-controlled studies. (2021) | SMD -0.119 [-0.302, 0.063] | 2 studies | Ungraded |
0-10 remaining teeth vs 25-32 remaining teeth Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of… (2021) | RR 2.65 [1.84, 3.81] | 4 studies · 193546 participants | High |
Intervention NR Prevalence of GERD/reflux (esophagitis or positive pH testing) · Adults with dental erosion Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review. (2020) | Four studies reported the prevalence of GERD/reflux findings among patients with dental erosion, ranging from 64% to 75% (Bartlett 64% pathological distal reflux; Gudmundsson 75% esophagitis; Wilder-Smith 69% GERD at… | 3 studies | Ungraded |
Juvenile idiopathic arthritis (JIA) vs Children and adolescents without JIA (healthy peers) Temporomandibular disorders (TMD), TMJ arthritis/involvement and orofacial pain · Children and adolescents with juvenile idiopathic arthritis (JIA) Oral health in children and adolescents with juvenile idiopathic arthritis - a systematic review and… (2019) | TMJ arthritis, TMJ involvement and TMD were coherently reported more frequently among children with JIA than healthy peers [35-38] (TMJ dysfunction also in [22]); e.g., higher frequency of condylar surface flattening… | 5 studies · 367 participants | Ungraded |
Learning disability (CLD) vs No learning disability (CNLD) Care index (CI), permanent teeth · Children aged 1-18 years Dental caries experience, care index and restorative index in children with learning disabilities and… (2019) | Mean care index CLD 0.12 (SD 0.12) vs CNLD 0.18 (SD 0.27) for permanent teeth; CI in CLD was less than or equal to CNLD in 5 of 8 studies. Not meta-analyzed (no variance data reported in any study). | 8 studies | Ungraded |
Learning disability (CLD) vs No learning disability (CNLD) Restorative index (RI), permanent teeth · Children aged 1-18 years Dental caries experience, care index and restorative index in children with learning disabilities and… (2019) | Mean restorative index CLD 0.15 (SD 0.14) vs CNLD 0.28 (SD 0.33) for permanent teeth; RI in CLD was less than or equal to CNLD in 4 of 9 studies. Not meta-analyzed (no variance data). In CLD the RI tended to exceed the… | 9 studies | Ungraded |
Juvenile idiopathic arthritis (JIA) vs Children and adolescents without JIA (healthy peers) Developmental enamel defects · Children and adolescents with juvenile idiopathic arthritis (JIA) Oral health in children and adolescents with juvenile idiopathic arthritis - a systematic review and… (2019) | The only study reporting developmental enamel defects [22] found the condition more frequent among children with JIA than healthy peers, but the sample size was too small to draw any reliable conclusion. | 1 study · 110 participants | Ungraded |
Juvenile idiopathic arthritis (JIA) vs Children and adolescents without JIA (healthy peers) Oral ulcerations · Children and adolescents with juvenile idiopathic arthritis (JIA) Oral health in children and adolescents with juvenile idiopathic arthritis - a systematic review and… (2019) | One study focused on oral ulceration [25] found five of forty-one children with JIA affected versus one of forty-one children without JIA. | 1 study · 82 participants | Ungraded |
Juvenile idiopathic arthritis (JIA) vs Children and adolescents without JIA (healthy peers) Dental maturation (tooth calcification) · Children and adolescents with juvenile idiopathic arthritis (JIA) Oral health in children and adolescents with juvenile idiopathic arthritis - a systematic review and… (2019) | Two studies gave divergent results: Lehtinen et al. [24] documented more advanced dental development in children with JIA, whereas Ley et al. [40] found dental maturity within the norms of healthy peers. | 2 studies | Ungraded |
Learning disability (CLD) vs No learning disability (CNLD) Unmet dental treatment need · Children aged 1-18 years Dental caries experience, care index and restorative index in children with learning disabilities and… (2019) | Six studies gave narrative reports of unmet dental need (Table 10); 5 of 6 reported greater unmet treatment need in CLD than CNLD, with no supporting numerical data. | 6 studies | Ungraded |
Juvenile idiopathic arthritis (JIA) vs Children and adolescents without JIA (healthy peers) Dental erosive wear · Children and adolescents with juvenile idiopathic arthritis (JIA) Oral health in children and adolescents with juvenile idiopathic arthritis - a systematic review and… (2019) | The present review lacked studies with focus on erosive wear; it concluded that for dental erosive wear there is no scientific evidence to answer the posed research questions. | 0 studies | No studies |
Dementia (any type or severity) vs Older people without dementia Retained roots (mean number) · Older people (aged 60 years or older) with dementia Oral health and orofacial pain in older people with dementia: a systematic review with focus on dental hard… (2017) | no estimate extracted | 3 studies | Ungraded |
Dementia (any type or severity) vs Older people without dementia Denture use (prevalence) · Older people (aged 60 years or older) with dementia Oral health and orofacial pain in older people with dementia: a systematic review with focus on dental hard… (2017) | no estimate extracted | 12 studies | Ungraded |
Dementia (any type or severity) vs Older people without dementia Edentulousness (prevalence) · Older people (aged 60 years or older) with dementia Oral health and orofacial pain in older people with dementia: a systematic review with focus on dental hard… (2017) | no estimate extracted | 11 studies | Ungraded |
Dementia (any type or severity) vs Older people without dementia Orofacial pain (prevalence) · Older people (aged 60 years or older) with dementia Oral health and orofacial pain in older people with dementia: a systematic review with focus on dental hard… (2017) | no estimate extracted | 7 studies | Ungraded |
Dementia (any type or severity) vs Older people without dementia Number of teeth present (mean) · Older people (aged 60 years or older) with dementia Oral health and orofacial pain in older people with dementia: a systematic review with focus on dental hard… (2017) | no estimate extracted | 16 studies | Ungraded |
Job-stress-related depression vs Women without depression Periodontitis and GCF IL-6 · Women on long-term sick leave for depression Social-Biological Interactions in Oral Disease: A 'Cells to Society' View. (2016) | no estimate extracted | 1 study · 49 participants | Ungraded |
Dementia vs Older people without dementia Decayed teeth · Older people with dementia Oral health and orofacial pain in older people with dementia: a systematic review with focus on dental hard… (2016) | MEAN Without dementia 0.0 to 2.9; with dementia 0.3 to 6.0 (mean number of decayed teeth) | 11 studies | Ungraded |
Dementia vs Older people without dementia Filled teeth · Older people with dementia Oral health and orofacial pain in older people with dementia: a systematic review with focus on dental hard… (2016) | MEAN Without dementia 0.7 to 25.7; with dementia 0.8 to 23.9 (mean number of filled teeth) | 9 studies | Ungraded |
Dementia vs Older people without dementia Missing teeth · Older people with dementia Oral health and orofacial pain in older people with dementia: a systematic review with focus on dental hard… (2016) | MEAN Without dementia 9.3 to 28.2; with dementia 10.2 to 27.3 (mean number of missing teeth) | 10 studies | Ungraded |