evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

3,323 questions · 5,762 findings · 263 reviews · Dental caries

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 321 · 5.6%GRADE not reported 4,450 · 77.2%Very low 455 · 7.9%Low 297 · 5.2%Moderate 200 · 3.5%High 39 · 0.7%

Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.

Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histology, excavation, or enhanced visual examination)

Sensitivity for detection of enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)

In the fully within-person analysis, visual classification had a summary sensitivity of 0.82 (95% CrI 0.73, 0.89); ungraded.

2 findings from 1 review

Food and nonalcoholic beverage marketing (exposure) vs No, less, or less powerful food marketing

Food intake · Children and adolescents (general population, aged under 20 years)

Food marketing was associated with a significant increase in children's food intake (pooled SMD, 0.25; combined RCT and nonrandomized evidence).

3 findings from 1 review

Resin-based fissure sealant vs Fluoride varnish

DMFS (decayed, missing, filled surfaces) increment, occlusal surfaces · Schoolchildren aged 6-12 years with sound occlusal surfaces of the first permanent molars

Pit and fissure sealant and fluoride varnish showed no statistically significant difference in DMFS increment at 24 months (SMD -0.13, 95% CI -0.67 to 0.40; I2=92%; not GRADE-rated).

1 finding from 1 review

Responsive complementary feeding (RCF) vs Other models of complementary feeding (traditional/non-responsive CF)

Overweight/obesity risk · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western industrialized countries

Responsive complementary feeding probably reduces the risk of overweight/obesity versus other feeding models (RR 0.41, 95% CI 0.24 to 0.71; moderate certainty).

1 finding from 1 review

High-viscosity GIC atraumatic restorative treatment vs No control

Restoration survival · Children with decayed primary molar teeth

Multi-surface ART restorations had a reported survival rate of 73% at 1 year.

4 findings from 1 review
Show 1 more finding

Composite strip crowns with composite, fiber, or reverse metal posts vs Alternative post type

Restoration failure · Children with carious primary teeth after vital or non-vital pulp therapy

In one RCT, composite strip crowns with composite posts had an annual failure rate of 2.3% after 1 year.

1 finding from 1 review

Dental caries assessment (WHO/clinical diagnostic criteria; caries = DMFT>0) vs None (descriptive prevalence review; subgroup analyses by urban/rural status, country and year)

Dental caries prevalence · 12-year-old children (permanent dentition) in Africa

Pooled caries prevalence in Uganda was 0.27 (95% CI 0.126 to 0.418; 3 article(s); not GRADE-rated).

23 findings from 1 review
Show 20 more findings

Resin-modified glass-ionomer cement (RMGIC) restoration vs Amalgam, compomer, composite resin, or glass carbomer

Treatment failure (annual failure rate) · Children with previously unrestored, vital carious lesions in primary teeth (no pulp therapy); aged 1.5-11 years

RMGIC had an annual failure rate of 1.9-16.9% (4 RCTs), lower than amalgam and similar to compomer/composite; low quality of evidence (ungraded).

1 finding from 1 review

Combined antiretroviral therapy (cART) vs Monotherapy or dual antiretroviral therapy

Dental caries prevalence and severity · Children and adolescents (<18 years) living with HIV (CLWH)

No significant difference in dental caries/severity between ART regimens (very low certainty).

1 finding from 1 review

Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls

Kaposi's sarcoma (WHO clinical stage 4) · Children or adolescents

No eligible studies reported Kaposi's sarcoma.

1 finding from 1 review

Pulpotomy (full or partial) vs None (single-arm pooled success proportion)

Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure

Among 6 observational studies, pooled pulpotomy success was 92.6 per 100 (95% CI 0.86-0.96), very low certainty.

4 findings from 1 review
Show 1 more finding

Responsive complementary feeding (RCF) vs usual care

Z score BMI · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western industrialized countries

In one RCT, responsive complementary feeding lowered BMIz at 13 months versus control (0.23 vs 0.42, p=0.01; low certainty).

1 finding from 1 review

Pulpotomy with Calcium Enriched Mixture (CEM) vs Pulpotomy with calcium hydroxide (Ca(OH)2)

Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure

CEM and calcium hydroxide did not differ significantly in pulpotomy success (indirect comparison); ungraded.

1 finding from 1 review

Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls

Salivary immunoglobulin A (SIgA) concentration · Children or adolescents

No significant difference in total salivary IgA between CLWH and healthy controls, though anti-Candida SIgA was higher in HIV groups; narrative only.

1 finding from 1 review

Food marketing exposure or greater marketing power vs No, less, or less powerful food marketing

Food choice · Children and adolescents (general population, aged under 20 years)

In crossover studies with binary outcomes, food marketing had no clear association with food choice (OR 3.45, 95% CI 0.97 to 12.43; ungraded).

1 finding from 1 review

Caries severity measurement (mean number of decayed, missing and filled permanent teeth, DMFT; WHO criteria) vs None (descriptive prevalence review; subgroup analyses by urban/rural status, country and year)

Dental caries · 12-year-old children (permanent dentition) in Africa

Pooled mean DMFT in Sudan was 0.49 (95% CI 0.461 to 0.519; 1 article(s); not GRADE-rated).

22 findings from 1 review
Show 19 more findings

Antiretroviral therapy (any, including cART) vs No antiretroviral medication (treatment-naive)

Linear gingival erythema prevalence · Children and adolescents (<18 years) living with HIV (CLWH)

No significant difference in linear gingival erythema between CLWH with and without ART (very low certainty).

1 finding from 1 review