Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,495 questions · 1,554 findings · 140 reviews · Heart

No studies found 272 · 17.5%GRADE not reported 44 · 2.8%Very low 329 · 21.2%Low 464 · 29.9%Moderate 319 · 20.5%High 126 · 8.1%

Intervention not reported

Maximum Plasma Creatine Phosphate · patients with acute coronary syndrome
1 finding from 1 review

Cells vs no cells

All‐cause mortality ‐ short‐term · Anyone diagnosed with AMI

Cells showed no clear difference in all‐cause mortality ‐ short‐term compared with no cells (moderate certainty).

1 finding from 1 review

Cells vs no cells

All‐cause mortality ‐ long‐term · Anyone diagnosed with AMI

Cells showed no clear difference in all‐cause mortality ‐ long‐term compared with no cells (moderate certainty).

1 finding from 1 review

Cells vs no cells

Cardiovascular mortality · Anyone diagnosed with AMI

Cells showed no clear difference in cardiovascular mortality ‐ short‐term compared with no cells (moderate certainty).

2 findings from 1 review

Cells vs no cells

Composite death, reinfarction and hospitalisation for heart failure ‐ short‐term · Anyone diagnosed with AMI

Cells showed no clear difference in composite death, reinfarction and hospitalisation for heart failure… compared with no cells (moderate certainty).

1 finding from 1 review

Cells vs no cells

Composite death, reinfarction and hospitalisation for heart failure ‐ long‐term · Anyone diagnosed with AMI

Cells showed no clear difference in composite death, reinfarction and hospitalisation for heart failure… compared with no cells (moderate certainty).

1 finding from 1 review

Aminophylline vs placebo

Survival to hospital discharge · participants with bradyasystolic cardiac arrest in adults

Aminophylline showed no clear difference in survival to hospital discharge compared with placebo (moderate certainty).

2 findings from 1 review

Aminophylline vs placebo

Return of spontaneous circulation · participants with bradyasystolic cardiac arrest in adults

Aminophylline showed no clear difference in return of spontaneous circulation compared with placebo (high certainty).

2 findings from 1 review

Aminophylline vs placebo

Early administration of aminophylline: survival to hospital admission · participants with bradyasystolic cardiac arrest in adults

Aminophylline showed no clear difference in survival to admission compared with placebo (moderate certainty).

2 findings from 1 review

Summary of findings ‐ structured telephone support or telemonitoring vs usual care

All‐cause mortality: Structured telephone support versus usual care · patients with heart failure

Summary of findings ‐ structured telephone support or telemonitoring probably leads to lower all‐cause mortality: Structured telephone support versus usual care compared with usual care ‐ all‐cause mortality (moderate certainty).

1 finding from 1 review

Summary of findings ‐ structured telephone support or telemonitoring vs usual care

Death (all causes) · patients with heart failure

Summary of findings ‐ structured telephone support or telemonitoring probably leads to lower all‐cause mortality: Telemonitoring versus usual care compared with usual care ‐ all‐cause mortality (moderate certainty).

1 finding from 1 review

Summary of findings ‐ structured telephone support or telemonitoring vs usual care ‐ all‐cause hospitalisation

Hospitalisation (any cause) · patients with heart failure

It is very uncertain whether summary of findings ‐ structured telephone support or telemonitoring changes all‐cause hospitalisation: Structured telephone support verus usual… compared with usual care ‐ all‐cause hospitalisation (very low certainty).

2 findings from 1 review

Summary of findings ‐ structured telephone support or telemonitoring vs usual care

Heart failure hospitalisation (RR) · patients with heart failure

Summary of findings ‐ structured telephone support or telemonitoring probably leads to lower CHF‐related hospitalisation: Structured telephone support versus… compared with usual care ‐ heart failure‐related hospitalisation (moderate certainty).

2 findings from 1 review

Fresh frozen plasma vs no plasma

Number of participants receiving a red cell transfusion (total) · Neonates, children and adults undergoing cardiovascular surgery

Fresh frozen plasma probably leads to higher number of patients receiving a red cell transfusion compared with no plasma (moderate certainty).

1 finding from 1 review

Fresh frozen plasma vs no plasma

Resource use: need for return to theatre · Neonates, children and adults undergoing cardiovascular surgery

Fresh frozen plasma showed no clear difference in resource use: need for return to theatre compared with no plasma (moderate certainty).

1 finding from 1 review