White spot lesions assessed by laser fluorescence (DIAGNOdent) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35)
Two studies found adhesive flash-free brackets did not clinically reduce enamel demineralization or white spot lesions versus conventional brackets, though they reduced pathogenic bacteria (ungraded).
1 finding from 1 review
Dental pain or sensitivity · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Recurrence · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects (tooth staining and other side effects) · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)
SDF commonly causes black staining of arrested lesions; only mild, transient adverse events were reported, with no major adverse events (ungraded).
1 finding from 1 review
Negative predictive value · Children and adults with primary or permanent dentition undergoing dental caries assessment
Negative predictive value was reported in 10 studies and ranged widely across studies (about 31% to 99.5%); no pooled estimate and certainty not graded.
1 finding from 1 review
Intervention not reported
Decayed surfaces (DS)
The intervention led to higher decayed surfaces (DS); GRADE not reported.
1 finding from 1 review
Change in probing pocket depth (PPD) · Adults (> 18 years) with recurrent periodontitis, receiving supportive (maintenance) periodontal care
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after… showed no clear difference in change in probing pocket depth (PPD) compared with subgingival instrumentation (SI) alone (hand or power-driven, or…; GRADE not reported.
2 findings from 1 review
Change in gingival recession (REC) · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
It is very uncertain whether adjunctive antimicrobial photodynamic therapy (aPDT) applied after… changes change in gingival recession (REC) compared with subgingival instrumentation (SI) alone (hand or power-driven, or… (very low certainty).
2 findings from 1 review
Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask after Alt-RAMEC showed no clear difference in overjet compared with facemask started simultaneously with Alt-RAMEC; GRADE not reported.
1 finding from 1 review
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
In 1 study, black or brown staining on treated lesions was more common after SDF (OR 3.19, 95% CI 1.95 to 5.23), with no other adverse effects. 1 study reported complaints of a transient bitter taste with SDF use (with…
3 studies · 980 participants
Very low
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Orthodontic removable traction appliance (ORTA) led to higher ANB compared with untreated control (no treatment); GRADE not reported.
1 finding from 1 review
Severity of joint noise · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Untreated dental caries (d component), continuous · Brazilian children/adolescents (BMI classified by WHO 2007 Z-score)
Obesity may make little or no difference to untreated dental caries (low certainty).
1 finding from 1 review
Early childhood caries (ECC) · Children aged 6 years or younger (preschool children)
Serum 25(OH)D <50 nmol/l (vs 50–75 nmol/l) was associated with higher odds of ECC (OR 1.47; ungraded).
1 finding from 1 review
Self-perceived (self-rated) oral health status · Adult residents of slums and non-slum urban settings of LMICs
Most participants perceive their oral health as satisfactory (one study 39%), more so among younger, male, higher-SES and employed people; ungraded.
1 finding from 1 review
Untreated dental caries (d component), continuous · Brazilian children/adolescents (BMI classified by WHO 2007 Z-score)
Overweight may make little or no difference to untreated dental caries (low certainty).
1 finding from 1 review
Alignment rate · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
1 finding from 1 review
Child oral health behaviours · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…
1 finding from 1 review
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask with rapid maxillary expansion (RME) led to lower ANB compared with mini maxillary protractor; GRADE not reported.
1 finding from 1 review
Adverse events for mother or child · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…
1 finding from 1 review