Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

962 questions · 1,000 findings · 69 reviews · Urology

No studies found 196 · 19.6%GRADE not reported 33 · 3.3%Very low 198 · 19.8%Low 354 · 35.4%Moderate 206 · 20.6%High 13 · 1.3%

Abiraterone + ADT vs ADT only

Discontinued treatment due to adverse events measured at a median · men with metastatic, hormone‐sensitive prostate cancer

Abiraterone + ADT probably leads to higher discontinued treatment due to adverse events measured at a median compared with ADT alone (moderate certainty).

1 finding from 1 review

Convective radiofrequency water vapour thermal therapy vs sham

Major adverse events · men with lower urinary tract symptoms suggesting benign prostatic hyperplasia

It is very uncertain whether convective radiofrequency water vapour thermal therapy changes major adverse events compared with sham procedure (very low certainty).

1 finding from 1 review

Convective radiofrequency water vapour thermal therapy vs sham

Retreatment · men with lower urinary tract symptoms suggesting benign prostatic hyperplasia

It is very uncertain whether convective radiofrequency water vapour thermal therapy changes retreatment compared with sham procedure (very low certainty).

1 finding from 1 review

Retzius‐sparing RALP vs standard RALP

Urinary continence within 1 week after catheter removal MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

Retzius‐sparing RALP probably leads to higher urinary continence within 1 week after catheter removal MCID: 5%… compared with standard RALP (moderate certainty).

1 finding from 1 review

Retzius‐sparing RALP vs standard RALP

Urinary continence 3 months after surgery MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

Retzius‐sparing RALP may leads to higher urinary continence 3 months after surgery MCID: 5% absolute difference compared with standard RALP (low certainty).

1 finding from 1 review

Retzius‐sparing RALP vs standard RALP

Serious adverse events · men (ages > 18 years) with clinically localized prostate cancer

It is very uncertain whether retzius‐sparing RALP changes serious adverse events compared with standard RALP (very low certainty).

1 finding from 1 review

Retzius‐sparing RALP vs standard RALP

Urinary continence 12 months after surgery MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

Retzius‐sparing RALP showed no clear difference in urinary continence 12 months after surgery MCID: 5% absolute… compared with standard RALP (moderate certainty).

1 finding from 1 review

Retzius‐sparing RALP vs standard RALP

Potency 12 months after surgery MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

It is very uncertain whether retzius‐sparing RALP changes potency 12 months after surgery MCID: 5% absolute difference compared with standard RALP (very low certainty).

1 finding from 1 review

Retzius‐sparing RALP vs standard RALP

Positive surgical margins MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

Retzius‐sparing RALP may leads to higher positive surgical margins MCID: 5% absolute difference compared with standard RALP (low certainty).

1 finding from 1 review

Retzius‐sparing RALP vs standard RALP

Biochemical recurrence‐free survival · men (ages > 18 years) with clinically localized prostate cancer

It is very uncertain whether retzius‐sparing RALP changes biochemical recurrence‐free survival compared with standard RALP (very low certainty).

1 finding from 1 review