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Light vibrational forces (LVF) showed no clear difference in patient perception of pain and discomfort (VAS 0 to 100 mm),… compared with conventional orthodontic appliance treatment (placebo or no adjunct) (low certainty).
The review found no eligible studies for this question.
Evidence on dentin bridge formation for calcium hydroxide versus MTA is weak and imprecise, with no material shown superior (4 RCTs, not pooled; ungraded).
In immature teeth, the effect of MTA versus calcium hydroxide on success is very uncertain (OR 2.22, 95% CI 0.13-36.67; very low certainty).
For direct pulp capping, MTA probably achieves higher clinical and radiographic success than calcium hydroxide (OR 3.10, 95% CI 1.66-5.79; moderate certainty).
When used to prevent white spot lesions on sound enamel, CPP-ACP pre-treatment did not significantly affect shear bond strength (MD 1.009, 95% CI -0.723 to 2.740; ungraded).
Operative treatment of caries lesions has a positive effect on OHRQoL in adolescents, though the included evidence was of low quality (narrative synthesis; no pooled estimate or GRADE rating by the umbrella review).
The review reported this model performance without meta-analysis.
Gum chewing reduced self-reported thirst in most studies (6 of 7 positive, 1 no effect); not meta-analyzed.
It is very uncertain whether CAD/CAM nitinol fixed (bonded) retainer changes survival of retainers (failure, lower arch) compared with conventional/analogue multistrand fixed (bonded) retainer (very low certainty).
Chlorhexidine mouthwash may reduce the Plaque Index versus blank control in the short term (WMD -0.70, 95% CI -1.12 to -0.27), but the evidence is very uncertain (very low certainty).
No difference in OHRQoL was seen between groups for periodontal disease by LOA on OHIP-14/OIDP (pooled SMD -0.04, CI includes 0); ungraded.
It is very uncertain whether full-time clear plastic (removable) retainer changes survival of retainers (failure, lower arch) compared with any type of fixed (bonded) retainer (very low certainty).
SDF+KI and RMGIC did not differ significantly for secondary caries prevention (p>0.05; ungraded).
Opposite effect directions were reported for MMP-9 by lesion depth or location (very low certainty).
Results were inconsistent and certainty was very low.
The association between baseline caries and declining height-for-age persisted after adjustment (coefficient -0.02); ungraded.
Integration strategies were generally associated with positive oral health knowledge, attitudes and perceptions among staff and patients (16 studies, narrative synthesis; ungraded).