Bacterial adhesion or initial colonization · Streptococcus mutans (in vitro cultures and biofilms)
No meta-analysis was conducted; three included studies reported reduced adhesion or initial colonization with cranberry extract or fractions.
1 finding from 1 review
no estimate extracted
3 studies
GRADE not reported
Caries experience (mean DMFT) · Brazilian children/adolescents in permanent dentition (BMI classified by CDC 2000 growth charts)
Normal-weight adolescents may have higher caries experience (DMFT) than obese peers in the permanent dentition, but the evidence is very uncertain (very low certainty).
1 finding from 1 review
Difficulty in swallowing (participant-reported proxy) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
Antioxidants (lycopene, curcumin, Oxitard) led to lower difficulty in swallowing (participant-reported proxy) compared with placebo or no active treatment; GRADE not reported.
1 finding from 1 review
Self-reported joint pain when chewing · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes self-reported joint pain when chewing compared with no treatment or placebo (non-occlusal or transparent-foil placebo… (very low certainty).
1 finding from 1 review
Alignment rate · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
1 finding from 1 review
Bacterial adhesion (inhibition) · Streptococcus mutans (in vitro cultures and biofilms)
Cranberry extract inhibits S. mutans adhesion / initial colonization in vitro (3 studies; ungraded).
1 finding from 1 review
High salivary S. mutans (over 10^4 CFU/ml) · adults
Salivary S. mutans showed a non-significant declining trend with periodontitis (OR 0.82).
1 finding from 1 review
OR 0.82 [0.44, 1.51]
2 studies
GRADE not reported
Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Chin cup led to higher wits appraisal compared with untreated control (no treatment); GRADE not reported.
1 finding from 1 review
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Nanda facemask led to higher ANB compared with conventional facemask; GRADE not reported.
1 finding from 1 review
Intervention not reported
Overall success (composite of clinical and radiographic success)
1 finding from 1 review
Oral health practices · Adult residents of slums and non-slum urban settings of LMICs
Toothbrush and toothpaste use was common, but lower in disadvantaged or slum populations where compared.
1 finding from 1 review
no estimate extracted
11 studies
GRADE not reported
Alignment rate · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
1 finding from 1 review
High salivary S. mutans (over 10^4 CFU/ml) · Periodontitis patients
High-level S. mutans did not change significantly after periodontal therapy (OR 1.54).
1 finding from 1 review
Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years
Fluoride toothpaste 440 ppm (lower concentration) probably leads to lower fluorosis (percentage prevalence in permanent teeth) compared with fluoride toothpaste 1450 ppm (higher concentration) (moderate certainty).
1 finding from 1 review
Dental pain or sensitivity · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Alignment rate · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
1 finding from 1 review
Multistrand StSt versus other materials (conventional StSt, superelastic NiTi, thermoelastic NiTi); alignment rate not pooled due to clinical heterogeneity (Cobb 1998; Evans 1998; Quintao 2005; West 1995); results…
4 studies · 281 participants
Very low
Child microbiological presence (mutans streptococci acquisition) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age
1 finding from 1 review
Early childhood caries (ECC) · Preschool children ≤6 years, Asia and Europe
In Asia and Europe, 25(OH)D 50–75 nmol/l (vs ≥75) was associated with higher odds of ECC (OR 1.32; ungraded).
1 finding from 1 review
Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask with rapid maxillary expansion (RME) led to lower wits appraisal compared with reverse Twin Block with lip pads and rapid maxillary expander (RME); GRADE not reported.
1 finding from 1 review
Dental caries prevalence · Brazilian children/adolescents (BMI classified by WHO 2007 percentile)
The evidence is very uncertain about the effect of overweight/obesity on caries odds (WHO 2007 percentile; very low certainty).
1 finding from 1 review