Death (before hospital discharge) or BPD (supplemental oxygen/respiratory support at 36 weeks' postmenstrual age if born < 32 weeks' gestation, or 28 days if born ≥ 32 weeks' gestation) · preterm infants requiring primary respiratory support
It is very uncertain whether nasal high flow changes death (before hospital discharge) or BPD (supplemental… compared with nasal intermittent positive pressure ventilation (very low certainty).
1 finding from 1 review
Mortality before hospital discharge · preterm infants requiring primary respiratory support
Nasal high flow showed no clear difference in death (before hospital discharge) compared with nasal intermittent positive pressure ventilation (low certainty).
1 finding from 1 review
Length of hospital stay · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
Adverse events Assessed by investigators or reported by parents · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
Clinical severity score (post‐treatment) at day 1 · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
Clinical severity score (post‐treatment) at day 2 · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
Clinical severity score (post‐treatment) at day 3 · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
Annual hospitalisation rates · infants up to 24 months of age with acute bronchiolitis
Nebulised hypertonic saline may leads to lower rate of hospitalisation compared with nebulised 0.9% saline (low certainty).
1 finding from 1 review
Hospital readmission · infants up to 24 months of age with acute bronchiolitis
Nebulised hypertonic saline showed no clear difference in rate of readmission to hospital compared with nebulised 0.9% saline (low certainty).
1 finding from 1 review
Number of days to resolution of symptoms and signs (wheezing) · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
Number of days to resolution of symptoms and signs (cough) · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
Number of days to resolution of symptoms and signs(pulmonary moist crackles) · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
Improved or corrected strabismusa at 6 or 12 months · adults and children with strabismus
Botulinum toxin may leads to lower improved or corrected strabismusa at 6 or 12 months compared with surgery (low certainty).
1 finding from 1 review
Serious adverse events at 6 or 12 months · adults and children with strabismus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of participants requiring additional surgery(ies) at 6 or 12 months · adults and children with strabismus
It is very uncertain whether botulinum toxin changes proportion of participants requiring additional surgery(ies) at 6 or… compared with surgery (very low certainty).
1 finding from 1 review
Proportion of participants who achieved binocular single vision at 6 or 12 months · adults and children with strabismus
Botulinum toxin showed no clear difference in proportion of participants who achieved binocular single vision at 6… compared with surgery (low certainty).
1 finding from 1 review
Quality of life (validated questionnaire) · adults and children with strabismus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Non‐serious adverse events at 6 or 12 months · adults and children with strabismus
1 finding from 1 review
Mean daily rating of problem severity (lower score is better) · women with premenstrual syndrome (most met DSM‐V criteria for premenstrual dysphoric disorder (PMDD))
1 finding from 1 review
Mean change in daily rating of functional impairment: reduction of productivity (lower score is better) · women with premenstrual syndrome (most met DSM‐V criteria for premenstrual dysphoric disorder (PMDD))
1 finding from 1 review