Nebulised hypertonic saline vs nebulised 0.9% saline: Annual hospitalisation rates
Nebulised hypertonic saline may leads to lower rate of hospitalisation compared with nebulised 0.9% saline (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Nebulised hypertonic saline vs nebulised 0.9% saline Rate of hospitalisation · infants up to 24 months of age with acute bronchiolitis Nebulised hypertonic saline may leads to lower rate of hospitalisation compared with nebulised 0.9% saline (low certainty). Nebulised hypertonic saline solution for acute bronchiolitis in infants (2023) · Cochrane Headline outcomes only | RR 0.87 [0.78, 0.97] | 8 studies · 1760 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Nebulised hypertonic saline solution for acute bronchiolitis in infants 2023 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.