Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,494 questions · 1,521 findings · 132 reviews · Hepato-Biliary

No studies found 303 · 19.9%GRADE not reported 39 · 2.6%Very low 876 · 57.6%Low 216 · 14.2%Moderate 65 · 4.3%High 22 · 1.4%

Summary of Findings Table ‐ Electrocoagulation alone vs control (vehicle solution of allopurinol by mouth)

All‐cause mortality at last · people with liver metastases

It is very uncertain whether summary of Findings Table ‐ Electrocoagulation alone changes all‐cause mortality at last compared with control (vehicle solution of allopurinol by mouth) (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Electrocoagulation alone vs control (vehicle solution of allopurinol by mouth)

Post‐operative deaths · people with liver metastases

It is very uncertain whether summary of Findings Table ‐ Electrocoagulation alone changes post‐operative deaths compared with control (vehicle solution of allopurinol by mouth) (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Electrocoagulation in combination with allopurinol or with dimethyl sulphoxide vs control (vehicle solution of allopurinol by mouth)

All‐cause mortality at last · people with liver metastases

Summary of Findings Table ‐ Electrocoagulation in combination with… may leads to lower all‐cause mortality at last compared with control (vehicle solution of allopurinol by mouth) (low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Electrocoagulation in combination with allopurinol or with dimethyl sulphoxide vs control (vehicle solution of allopurinol by mouth)

Post‐operative deaths · people with liver metastases

It is very uncertain whether summary of Findings Table ‐ Electrocoagulation in combination with… changes post‐operative deaths compared with control (vehicle solution of allopurinol by mouth) (very low certainty).

1 finding from 1 review

Band ligation vs no intervention or a sham procedure

All‐cause mortality · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

It is very uncertain whether band ligation changes all‐cause mortality compared with sham or no intervention (very low certainty).

1 finding from 1 review

Band ligation vs no intervention or a sham procedure

Serious adverse events Idiopathic thrombocytopaenic purpura · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

It is very uncertain whether band ligation changes serious adverse events Idiopathic thrombocytopaenic purpura compared with sham or no intervention (very low certainty).

1 finding from 1 review

Band ligation vs no intervention or a sham procedure

Health‐related quality of life · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

The review found no eligible studies for this question.

1 finding from 1 review

Band ligation vs no intervention or a sham procedure

Oesophageal variceal bleeding · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

It is very uncertain whether band ligation changes oesophageal variceal bleeding compared with sham or no intervention (very low certainty).

1 finding from 1 review

Band ligation vs no intervention or a sham procedure

Adverse events considered non‐serious · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

The review found no eligible studies for this question.

1 finding from 1 review