Cochrane · systematic review · CD009497

Electrocoagulation for liver metastases

Storman, D, Swierz, MJ, Riemsma, RP, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
4
No studies
6
Included studies
NR
No studies 6 · 60%Ungraded 0 · 0%Very low 3 · 30%Low 1 · 10%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of Findings Table ‐ Electrocoagulation alone compared to control (vehicle solution of allopurinol by mouth) for people with liver metastases

Population: people with liver metastases
5 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality at last
Summary of Findings Table ‐ Electrocoagulation alone vs control (vehicle solution of allopurinol by mouth)
RR 0.98 [0.94, 1.03]1 study · 113 participantsVery low
Downgraded: risk of bias, imprecision
Post‐operative deaths
Summary of Findings Table ‐ Electrocoagulation alone vs control (vehicle solution of allopurinol by mouth)
RR 1.03 [0.07, 16.12]1 study · 152 participantsVery low
Downgraded: risk of bias, imprecision
Other adverse events and complications
Summary of Findings Table ‐ Electrocoagulation alone vs control (vehicle solution of allopurinol by mouth)
no estimate extractedNRNo studies
Failure to clear liver metastases or recurrence of liver metastases
Summary of Findings Table ‐ Electrocoagulation alone vs control (vehicle solution of allopurinol by mouth)
no estimate extractedNRNo studies
Tumour response
Summary of Findings Table ‐ Electrocoagulation alone vs control (vehicle solution of allopurinol by mouth)
no estimate extractedNRNo studies

Summary of Findings Table ‐ Electrocoagulation in combination with allopurinol or with dimethyl sulphoxide compared to control (vehicle solution of allopurinol by mouth) for people with liver metastases

Population: people with liver metastases
5 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality at last
Summary of Findings Table ‐ Electrocoagulation in combination with allopurinol or with dimethyl sulphoxide vs control (vehicle solution of allopurinol by mouth)
RR 0.87 [0.8, 0.95]1 study · 165 participantsLow
Downgraded: risk of bias, imprecision
Post‐operative deaths
Summary of Findings Table ‐ Electrocoagulation in combination with allopurinol or with dimethyl sulphoxide vs control (vehicle solution of allopurinol by mouth)
RR 0.99 [0.09, 11.06]1 study · 231 participantsVery low
Downgraded: risk of bias, imprecision
Other adverse events and complications
Summary of Findings Table ‐ Electrocoagulation in combination with allopurinol or with dimethyl sulphoxide vs control (vehicle solution of allopurinol by mouth)
no estimate extractedNRNo studies
Failure to clear liver metastases or recurrence of liver metastases
Summary of Findings Table ‐ Electrocoagulation in combination with allopurinol or with dimethyl sulphoxide vs control (vehicle solution of allopurinol by mouth)
no estimate extractedNRNo studies
Tumour response
Summary of Findings Table ‐ Electrocoagulation in combination with allopurinol or with dimethyl sulphoxide vs control (vehicle solution of allopurinol by mouth)
no estimate extractedNRNo studies