Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

38 questions · 40 findings · 13 reviews · Wounds

No studies found 6 · 15%GRADE not reported 1 · 2.5%Very low 19 · 47.5%Low 8 · 20%Moderate 5 · 12.5%High 1 · 2.5%

Summary of findings table ‐ Off‐midline closure vs tension‐free midline closure

Wound infection · pilonidal sinus

It is very uncertain whether summary of findings table ‐ Off‐midline closure changes wound infection compared with tension‐free midline closure (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Off‐midline closure (Karydakis flap) vs off‐midline closure (Limberg flap)

Wound infection · pilonidal sinus

Summary of findings table ‐ Off‐midline closure (Karydakis flap) showed no clear difference in wound infection compared with off‐midline closure (Limberg flap) (low certainty).

1 finding from 1 review

Hydrogel dressings vs manuka honey

Wound infection · people with venous leg ulcers

It is very uncertain whether hydrogel dressings changes incidence of wound infection compared with manuka honey (very low certainty).

1 finding from 1 review