Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

192 questions · 196 findings · 89 reviews

No studies found 31 · 15.8%GRADE not reported 18 · 9.2%Very low 68 · 34.7%Low 48 · 24.5%Moderate 24 · 12.2%High 7 · 3.6%

Belimumab 10 mg/kg vs placebo

Withdrawals due to adverse events · people with active systemic lupus erythematosus (but not active nephritis or active central nervous system involvement)

Belimumab 10 mg/kg showed no clear difference in withdrawals due to adverse events compared with placebo (moderate certainty).

1 finding from 1 review

All doses of cerivastatin vs placebo

Withdrawals due to adverse events · participants with normal or abnormal lipid profiles

It is very uncertain whether all doses of cerivastatin changes withdrawals due to adverse events compared with placebo (very low certainty).

1 finding from 1 review

Adalimumab vs placebo

Withdrawals due to adverse events · Participants with Crohn's disease in remission

Adalimumab probably leads to lower withdrawals due to adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Anti‐TNF discontinuation vs anti‐TNF continuation

Withdrawals due to adverse events · people with rheumatoid arthritis with low disease activity using a standard dose of anti‐TNF agents

Anti‐TNF discontinuation showed no clear difference in withdrawals due to adverse events compared with anti‐TNF continuation (moderate certainty).

1 finding from 1 review

Anti‐TNF dose reduction vs anti‐TNF continuation

Withdrawals due to adverse events · people with rheumatoid arthritis with low disease activity using a standard dose of anti‐TNF agents

Anti‐TNF dose reduction showed no clear difference in withdrawals due to adverse events compared with anti‐TNF continuation (low certainty).

1 finding from 1 review