Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

52 questions · 52 findings · 24 reviews · Haematology

No studies found 12 · 23.1%GRADE not reported 0 · 0%Very low 16 · 30.8%Low 18 · 34.6%Moderate 6 · 11.5%High 0 · 0%

Anti‐leukaemic therapy plus alemtuzumab vs anti‐leukaemic therapy alone (anti‐leukaemic therapy identical

Serious adverse events · people with chronic lymphocytic leukaemia

Anti‐leukaemic therapy plus alemtuzumab showed no clear difference in serious adverse events compared with anti‐leukaemic therapy alone (anti‐leukaemic therapy identical (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Convalescent plasma vs placebo or usual care

Serious adverse events ‐ total · individuals with moderate to severe disease

Summary of findings table ‐ Convalescent plasma showed no clear difference in serious adverse events ‐ total compared with placebo or standard care alone (moderate certainty).

1 finding from 1 review