Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

143 questions · 149 findings · 66 reviews · Airways

No studies found 27 · 18.1%GRADE not reported 8 · 5.4%Very low 19 · 12.8%Low 39 · 26.2%Moderate 41 · 27.5%High 15 · 10.1%

Reslizumab intravenous (IV) vs placebo

Serious adverse events · people with asthma

Reslizumab intravenous (IV) showed no clear difference in serious adverse events compared with placebo (high certainty).

1 finding from 1 review

Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP)

Serious adverse events

The review found no eligible studies for this question.

2 findings from 1 review

Adaptive servo ventilation (ASV) vs bilevel ventilation

Serious adverse events

The review found no eligible studies for this question.

2 findings from 1 review

Inhaled corticosteroids plus standard care vs placebo or usual care

Serious adverse events · adults with a confirmed diagnosis of mild COVID‐19, of whom only 10% (219/2132) participants had received ≥ 1 vaccination

It is very uncertain whether inhaled corticosteroids plus standard care changes serious adverse events compared with standard care (with or without placebo) (very low certainty).

1 finding from 1 review