Question · asked by 1 review

Reslizumab subcutaneous (SC) vs placebo: Serious adverse events

Reslizumab subcutaneous (SC) showed no clear difference in serious adverse events compared with placebo (high certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Reslizumab subcutaneous (SC) vs placebo
Serious adverse events · people with asthma
Reslizumab subcutaneous (SC) showed no clear difference in serious adverse events compared with placebo (high certainty).
Anti‐IL‐5 therapies for asthma (2022) · Cochrane Headline outcomes only
Risk ratio 0.97 [0.53, 1.79]1 study · 464 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Anti‐IL‐5 therapies for asthma
2022 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.