What do systematic reviews say?

Intralesional pentoxifylline vs daily simple dressing

The review found no eligible studies for this question.

• Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Light‐emitting diode (LED) irradiation vs standard dressing

The review found no eligible studies for this question.

• Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Wax therapy vs foot soaks

The review found no eligible studies for this question.

• Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

hAMMSC‐CM + vitamin C vs hAMMSC‐CM

The review found no eligible studies for this question.

• Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

hAMMSC‐CM + vitamin E vs hAMMSC‐CM

The review found no eligible studies for this question.

• Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

hAMMSC‐CM + vitamin E vs hAMMSC‐CM + vitamin C

The review found no eligible studies for this question.

• Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)

• Primary cryotherapy for localised or locally advanced prostate cancer 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 195 participants
  Very low

Prosthetic mesh placement vs usual care

• Prosthetic mesh placement for the prevention of parastomal herniation 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 263 participants
  GRADE not reported

Endovascular revascularisation vs conservative therapy

• Endovascular revascularisation versus conservative management for intermittent claudication 2018 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 301 participants
  High

Endovascular revascularisation plus conservative therapy vs conservative therapy

• Endovascular revascularisation versus conservative management for intermittent claudication 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 330 participants
  Moderate

Endovascular revascularisation vs no therapy

The review found no eligible studies for this question.

• Endovascular revascularisation versus conservative management for intermittent claudication 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

EHealth interventions vs any comparator

• E‐Health interventions for anxiety and depression in children and adolescents with long‐term physical conditions 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 34 participants
  Very low

One‐incision vs two‐incision techniques

The review found no eligible studies for this question.

• One‐incision versus two‐incision techniques for arthroscopically assisted anterior cruciate ligament reconstruction in… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

• Acupuncture for neck disorders 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 178 participants
  Low

Decreasing fluids vs increasing fluids

• Lifestyle interventions for the treatment of urinary incontinence in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 69 participants
  Very low

Intermittent ICS vs placebo

• Intermittent inhaled corticosteroid therapy versus placebo for persistent asthma in children and adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 143 participants
  Low

Intervention not reported

• Continuous glucose monitoring systems for type 1 diabetes mellitus 2012 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 412 participants
  GRADE not reported

Oral azithromycin vs placebo

• Macrolide antibiotics (including azithromycin) for cystic fibrosis 2024 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 177 participants
  Moderate

Toothache vs No toothache

The umbrella review reported that toothache has a high impact on oral health-related quality of life.

• Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
  no estimate extracted
  Studies not reported
  GRADE not reported

Dental (tooth) agenesis vs No dental agenesis

The umbrella review reported insufficient scientific evidence to support an association between dental agenesis and oral health-related quality of life.

• Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
  no estimate extracted
  Studies not reported
  GRADE not reported
• Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes

  Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
  tooth agenesis does not have enough scientific evidence to support a relationship between OHRQoL [41]. No articles were found that had evaluated children and adolescent. Only one was found to have a greater impact in…
  Studies not reported
  GRADE not reported