Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,241 questions · 3,336 findings · 1,340 reviews

No studies found 1,581 · 47.4%GRADE not reported 352 · 10.6%Very low 512 · 15.3%Low 509 · 15.3%Moderate 316 · 9.5%High 66 · 2%

Dornase alfa vs alternate days

Mean relative percentage in quality of life score at 3 months · children with cystic fibrosis

Dornase alfa daily showed no clear difference in mean relative percentage in quality of life score at 3 months compared with alternate days (low certainty).

1 finding from 1 review

Dornase alfa vs hypertonic saline

Mean relative percentage in quality of life score at 3 months · children with cystic fibrosis

Dornase alfa showed no clear difference in mean relative percentage in quality of life score at 3 months compared with hypertonic saline (low certainty).

1 finding from 1 review

Edentulism (complete or partial missing teeth) vs Individuals without edentulism

Oral health-related quality of life · Indian elderly

One study found edentulism did not affect OHRQoL (dichotomous); ungraded.

3 findings from 1 review

Malocclusion vs No malocclusion

Oral health-related quality of life · Indian children, adolescents and adults

One GOHAI study found no significant difference in OHRQoL by malocclusion status; ungraded.

3 findings from 1 review

Dental caries vs Caries-free controls

Oral health-related quality of life · Indians

In adolescents (10-19 years), dental caries was associated with poorer OHRQoL (pooled OR 3.92; 5 studies); ungraded.

5 findings from 1 review
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Periodontal disease assessed by loss of attachment (LOA / clinical attachment loss) vs Individuals without periodontal disease (by LOA)

Oral health-related quality of life · Indian adults and elderly (general, police, teachers, institutionalised)

No difference in OHRQoL was seen between groups for periodontal disease by LOA on OHIP-14/OIDP (pooled SMD -0.04, CI includes 0); ungraded.

3 findings from 1 review

Periodontal disease assessed by Community Periodontal Index (CPI) vs Individuals without periodontal disease (by CPI)

Oral health-related quality of life · Indian adults and elderly (general, police, teachers, institutionalised)

Evidence on periodontal disease (CPI) and OHRQoL is inconsistent across studies (very low certainty).

3 findings from 1 review

Gingivitis (assessed by gingival index or WHO criteria) vs Individuals without gingivitis

Oral health-related quality of life · Indians

Continuous analyses (GOHAI, OHIP-14) of gingivitis and OHRQoL were inconsistent and mostly non-significant; ungraded.

2 findings from 1 review

Prosthetic need vs Individuals without prosthetic need

Oral health-related quality of life · Indian elderly and general-population adults

Prosthetic need was significantly associated with poorer OHRQoL in both included studies (moderate certainty).

3 findings from 1 review

0-19 remaining teeth vs Individuals without functional edentulism

Oral health-related quality of life · Indian elderly

Evidence on functional edentulism and OHRQoL is inconsistent across two studies (very low certainty).

2 findings from 1 review