What do systematic reviews say?

Female gender (girls) vs Male gender (boys)

Girls had modestly higher odds of poor OHRQoL than boys (OR 1.13, 95% CI 1.09-1.17; 3 studies; ungraded).

• The Association of Oral Health Status, demographic characteristics and socioeconomic determinants with Oral… 2020 All outcomes

  Upper-middle-income countries (Brazil); studies 2010-2013
  OR 1.13 [1.09, 1.17]
  3 studies
  GRADE not reported

Higher dental caries experience vs Caries-free controls

Higher dental caries experience was associated with substantially higher odds of poor OHRQoL (OR 1.66, 95% CI 1.43-1.88; 6 studies; high heterogeneity I2=83.5%; ungraded).

• The Association of Oral Health Status, demographic characteristics and socioeconomic determinants with Oral… 2020 All outcomes

  Upper-middle-income countries (5 studies) and one high-income country; studies 2011-2017
  OR 1.66 [1.43, 1.88]
  6 studies
  GRADE not reported

Pharmacological interventions vs placebo/usual care or different forms of intervention

The review found no eligible studies for this question.

• Interventions for sexual dysfunction following stroke 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Sorafenib vs pazopanib (targeted agent versus targeted agent)

• Targeted therapy for metastatic renal cell carcinoma 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 267 participants
  Low

Exercise vs usual care

• Exercise therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 136 participants
  Very low

Low maternal education (<=6 years of schooling) vs Higher maternal education (>6 years)

Lower maternal education was associated with poor OHRQoL (OR 1.12, 95% CI 1.00-1.23; 4 studies; high heterogeneity; CI lower bound at the null; ungraded).

• The Association of Oral Health Status, demographic characteristics and socioeconomic determinants with Oral… 2020 All outcomes

  Upper-middle-income countries; studies 2010-2014
  OR 1.12 [1.00, 1.23]
  4 studies
  GRADE not reported

Orthodontic treatment need vs No orthodontic treatment need

Orthodontic treatment need was associated with modestly higher odds of poor OHRQoL (OR 1.13, 95% CI 1.07-1.18; 3 studies; ungraded).

• The Association of Oral Health Status, demographic characteristics and socioeconomic determinants with Oral… 2020 All outcomes

  Upper-middle-income countries (Brazil); studies 2012-2019
  OR 1.13 [1.07, 1.18]
  3 studies
  GRADE not reported

Deep brain stimulation vs sham stimulation

• Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 62 participants
  Very low

Reminiscence therapy vs no treatment

• Reminiscence therapy for dementia 2018 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 1060 participants
  Moderate

Intervention not reported

The review found no eligible studies for this question.

• Restriction of salt, caffeine and alcohol intake for the treatment of Ménière's disease or syndrome 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pembrolizumab vs chemotherapy alone

Pembrolizumab may leads to higher quality of life (Change from baseline to week 15) compared with chemotherapy (low certainty).

• Pembrolizumab monotherapy versus chemotherapy for treatment of advanced urothelial carcinoma with disease progression… 2018 · Cochrane Headline outcomes only
  MD 9.05 [4.61, 13.5]
  1 study · 519 participants
  Low

Communication skills training vs no specific training

The review found no eligible studies for this question.

• Communication skills training for mental health professionals working with people with severe mental illness 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

SPRM vs placebo

• Selective progesterone receptor modulators (SPRMs) for uterine fibroids 2017 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 171 participants
  Moderate

SPRM vs leuprolide acetate

• Selective progesterone receptor modulators (SPRMs) for uterine fibroids 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 281 participants
  Moderate

Active cancer therapy combined with TCM vs active cancer therapy

Active cancer therapy combined with TCM may leads to higher quality of life ‐ number experiencing improvement compared with active cancer therapy (low certainty).

• Chinese herbal medicine for oesophageal cancer 2016 · Cochrane Headline outcomes only
  RR 2.2 [1.42, 3.39]
  5 studies · 233 participants
  Low

Soy‐rich diet vs control

The review found no eligible studies for this question.

• Lifestyle interventions for the treatment of urinary incontinence in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Lifestyle weight loss vs metformin weight loss

The review found no eligible studies for this question.

• Lifestyle interventions for the treatment of urinary incontinence in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

PFMT added to lifestyle intervention vs lifestyle intervention alone

The review found no eligible studies for this question.

• Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: ACBT vs exercise

• Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 19 participants
  Very low

Cephalomedullary nails vs extramedullary implants

The review found no eligible studies for this question.

• Cephalomedullary nails versus extramedullary implants for extracapsular hip fractures in older adults 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found