What do systematic reviews say?

Physical activity vs usual care

• Physical activity interventions for disease‐related physical and mental health during and following treatment in… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 230 participants
  Moderate

Summary of findings for the main comparison. Physical activity and exercise interventions vs usual care

• Physical activity interventions for people with congenital heart disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 163 participants
  Very low

Smart technology vs face‐to‐face/digital and/or written support

• Computer and mobile technology interventions for self‐management in chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 472 participants
  Low

Self‐management interventions vs usual care

• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 1582 participants
  High

Follow‐up integrating additional patient symptom education or monitoring, or survivorship care plans vs usual care

• Follow‐up strategies following completion of primary cancer treatment in adult cancer survivors 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Exercise vs no exercise

• Exercise‐based cardiac rehabilitation for adult patients with an implantable cardioverter defibrillator 2019 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 433 participants
  Very low

Summary of findings table ‐ Systemic therapy vs control

• Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 208 participants
  Very low

Complex information, support and training interventions vs inactive control (usual care care, attention control, waitlist)

• Remotely delivered information, training and support for informal caregivers of people with dementia 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 311 participants
  Moderate

Complex information, support and training interventions vs information only

• Remotely delivered information, training and support for informal caregivers of people with dementia 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 257 participants
  Low

NSAIDs vs glucocorticoids

The review found no eligible studies for this question.

• Non‐steroidal anti‐inflammatory drugs for acute gout 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Metformin + megestrol vs megestrol

The review found no eligible studies for this question.

• Metformin for endometrial hyperplasia 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Metformin vs megestrol

The review found no eligible studies for this question.

• Metformin for endometrial hyperplasia 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Exercise vs no exercise

• Exercise‐based cardiac rehabilitation in heart transplant recipients 2017 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 120 participants
  Moderate

Lateral wedge insole vs neutral insole

• Braces and orthoses for treating osteoarthritis of the knee 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 179 participants
  Moderate

Intervention not reported

• Braces and orthoses for treating osteoarthritis of the knee 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 179 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in health‐related quality of life (HRQOL) disease‐specific HRQOL (low certainty).

• Positive expiratory pressure therapy versus other airway clearance techniques for bronchiectasis 2017 · Cochrane Headline outcomes only
  no estimate extracted
  17 participants
  Low

Flutamide 250 mg once to b.i.d. vs spironolactone 100 mg

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Spironolactone 100 mg vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg to 7.5 mg vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found