What do systematic reviews say?

Flexibility exercise training vs aerobic exercise training

• Flexibility exercise training for adults with fibromyalgia 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 193 participants
  Very low

Intervention not reported

The review found no eligible studies for this question.

• Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Valgus knee brace vs lateral wedge insole

The review found no eligible studies for this question.

• Braces and orthoses for treating osteoarthritis of the knee 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Rituximab (2 x 1000 mg) plus methotrexate vs methotrexate

Rituximab (2 x 1000 mg) plus methotrexate leads to higher health‐related quality of life compared with methotrexate monotherapy (high certainty).

• Rituximab for rheumatoid arthritis 2015 · Cochrane Headline outcomes only
  RR 2 [1.1, 3.4]
  4 studies · 1526 participants
  High

Preoperative education vs usual care

The review found no eligible studies for this question.

• Preoperative education for hip or knee replacement 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Erythropoietin (subcutaneous or intravenous at varying dosages) vs placebo

• Erythropoiesis‐stimulating agents for anemia in rheumatoid arthritis 2013 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 136 participants
  Very low

Intervention not reported

The review found no eligible studies for this question.

• Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Other types of high tibial osteotomy (aHTO) vs closing wedge high tibial osteotomy (CW‐HTO)

The review found no eligible studies for this question.

• Osteotomy for treating knee osteoarthritis 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Uncemented fixation with and without hydroxyapatite vs cemented fixation

• Cemented, cementless or hybrid fixation options in total knee arthroplasty for osteoarthritis and other non‐traumatic… 2012 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Autologous blood or PRP vs placebo at 3 months' follow‐up

• Autologous blood and platelet‐rich plasma injection therapy for lateral elbow pain 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Intervention not reported

• Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 81 participants
  Very low

Methotrexate vs other DMARDs

The review found no eligible studies for this question.

• Methotrexate for psoriatic arthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Methotrexate vs placebo

The review found no eligible studies for this question.

• Methotrexate for psoriatic arthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Rilonacept vs indomethacin

The review found no eligible studies for this question.

• Interleukin‐1 inhibitors for acute gout 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Canakinumab vs triamcinolone acetonide

The review found no eligible studies for this question.

• Interleukin‐1 inhibitors for acute gout 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Lifestyle interventions for acute gout 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NSAIDs vs glucocorticoids

The review found no eligible studies for this question.

• Non‐steroidal anti‐inflammatory drugs for acute gout 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The intervention showed no clear difference in health‐Related Quality of Life at least 20% improvement (moderate certainty).

• Methotrexate for treating rheumatoid arthritis 2014 · Cochrane Headline outcomes only
  RR 1.5 [1, 2.1]
  1 study · 263 participants
  Moderate

Valgus knee brace vs no brace

• Braces and orthoses for treating osteoarthritis of the knee 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 117 participants
  Low

Lateral wedge insole vs neutral insole

• Braces and orthoses for treating osteoarthritis of the knee 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 179 participants
  Moderate