Summary of findings table ‐ Any psychosocial intervention leads to lower dropouts compared with no intervention (high certainty).
Summary of findings table ‐ Any psychosocial intervention leads to lower dropouts compared with treatment (high certainty).
It is very uncertain whether baclofen changes dropouts compared with diazepam (very low certainty).
It is very uncertain whether baclofen changes dropouts compared with chlordiazepoxide (very low certainty).
The review found no eligible studies for this question.
Any dopamine agonist showed no clear difference in dropouts compared with placebo (moderate certainty).
Amantidine showed no clear difference in dropouts compared with antidepressants (moderate certainty).
Amantadine showed no clear difference in dropouts compared with placebo (moderate certainty).
Anticonvulsants showed no clear difference in dropouts compared with placebo (moderate certainty).
Benzodiazepine showed no clear difference in dropouts compared with placebo (moderate certainty).
It is very uncertain whether baclofen changes dropouts due to AEs compared with diazepam (very low certainty).
It is very uncertain whether baclofen changes dropouts due to AEs compared with chlordiazepoxide (very low certainty).
The review found no eligible studies for this question.
Antidepressants showed no clear difference in acceptability: dropouts compared with placebo: all studies (low certainty).
It is very uncertain whether summary of findings table ‐ Baclofen changes dropouts at end of treatment compared with acamprosate (very low certainty).
It is very uncertain whether summary of findings table ‐ Baclofen changes dropouts at end of treatment compared with naltrexone (very low certainty).
Summary of findings table ‐ Baclofen showed no clear difference in dropouts at end of treatment compared with placebo (high certainty).
It is very uncertain whether summary of findings table ‐ Baclofen changes dropouts due to adverse events compared with acamprosate (very low certainty).
Summary of findings table ‐ Baclofen showed no clear difference in dropouts due to adverse events compared with placebo (high certainty).
Any Psychosocial plus any Pharmacological probably leads to lower dropouts ‐ All studies objective compared with any Pharmachological alone compared to (moderate certainty).