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What do systematic reviews say?

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Evidence found and GRADE certainty

1,337 questions · 1,354 findings · 566 reviews

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No studies found 307 · 22.7%GRADE not reported 81 · 6%Very low 424 · 31.3%Low 310 · 22.9%Moderate 189 · 14%High 43 · 3.2%

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with treating osteoarthritis
1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with treating osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with osteoarthritis

The intervention showed no clear difference in adverse events Participants (n) reported serious adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with treating osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Persea gratissma + Glycine max (ASU 300 mg) vs chondroitin sulphate

Adverse events Participants (n) reported serious adverse events · patients with osteoarthritis

Persea gratissma + Glycine max (ASU 300 mg) showed no clear difference in adverse events Participants (n) reported serious adverse events compared with chondroitin sulphate (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with osteoarthritis of the knee

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with osteoarthritis of the knee

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events (serious ‐ resulting in hospitalisation or death) · adults aged ≥ 18 years with a diagnosis of glenohumeral osteoarthritis who have not responded to non‐operative treatments
1 finding from 1 review

Acupuncture vs no intervention

Proportion of participants with 1 or more serious adverse events · chronic hepatitis B

The review found no eligible studies for this question.

1 finding from 1 review

Terlipressin vs other vasoactive drugs

Non‐serious adverse events: diarrhoea or abdominal pain, or both · people with cirrhosis and hepatorenal syndrome

It is very uncertain whether terlipressin changes non‐serious adverse events: diarrhoea or abdominal pain, or both compared with other vasoactive drugs (very low certainty).

1 finding from 1 review

Methylphenidate vs placebo or no intervention

Proportion of participants with one or more serious adverse events · Children and adolescents with ADHD

It is very uncertain whether methylphenidate changes proportion of participants with one or more serious adverse events compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Sublingual immunotherapy vs control

Serious adverse events Weighted mean duration of studies: 49 weeks · people with asthma

Sublingual immunotherapy showed no clear difference in serious adverse events Weighted mean duration of studies: 56 weeks compared with control (moderate certainty).

1 finding from 1 review