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Hypertonic saline showed no clear difference in adverse events compared with isotonic saline; GRADE not reported.
Inhaled mannitol showed no clear difference in adverse events compared with placebo (moderate certainty).
Liposomal daunorubicin showed no clear difference in adverse events compared with ABV (moderate certainty).
It is very uncertain whether bleomycin changes adverse events compared with ABV (very low certainty).
HAART + ABV showed no clear difference in adverse events compared with HAART alone (moderate certainty).
It is very uncertain whether closing wedge high tibial osteotomy (CW‐HTO) changes adverse events compared with unicompartmental knee arthroplasty (very low certainty).
The intervention showed no clear difference in adverse events (low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
The review found no eligible studies for this question.
It is very uncertain whether neoadjuvant immunotherapy (talimogene laherparepvec) changes adverse Events, compared with no neoadjuvant treatment (very low certainty).
Neoadjuvant immunotherapy (combined ipilimumab and nivolumab) showed no clear difference in adverse events, compared with adjuvant immunotherapy (combined ipilimumab and nivolumab) (low certainty).
It is very uncertain whether neoadjuvant treatment changes adverse events, compared with no neoadjuvant treatment (very low certainty).
It is very uncertain whether neoadjuvant immunotherapy (combined ipilimumab and nivolumab) changes adverse events, compared with neoadjuvant immunotherapy (nivolumab) (very low certainty).