Findings

What do systematic reviews say?

4,918 questions · 5,537 findings · 1,803 reviews

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No studies found 1,309 · 23.6%GRADE not reported 440 · 7.9%Very low 1,560 · 28.2%Low 1,292 · 23.3%Moderate 751 · 13.6%High 185 · 3.3%

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Modafinil vs placebo

Adverse events · people with postpolio syndrome

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 50 participants
GRADE not reported

Pyridostigmine vs placebo

Adverse events · people with postpolio syndrome

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 193 participants
GRADE not reported

Lamotrigine vs control

Adverse events · people with postpolio syndrome

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
GRADE not reported

Recombinant human soluble thrombomodulin vs heparin

Adverse events · DIC

It is very uncertain whether recombinant human soluble thrombomodulin changes adverse events compared with heparin (very low certainty).

1 finding from 1 review

Treatment for disseminated intravascular coagulation in patients with acute and chronic leukemia 2015 · Cochrane Headline outcomes only
RR 0.88 [0.35, 2.2]
1 study · 231 participants
Very low

Tranexamic acid vs placebo

Adverse events · DIC

1 finding from 1 review

Treatment for disseminated intravascular coagulation in patients with acute and chronic leukemia 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Very low

Dermatan vs heparin

Adverse events · DIC

1 finding from 1 review

Treatment for disseminated intravascular coagulation in patients with acute and chronic leukemia 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 10 participants
Very low

Human activated protein C vs heparin

Adverse events · DIC

It is very uncertain whether human activated protein C changes adverse events compared with heparin (very low certainty).

1 finding from 1 review

Treatment for disseminated intravascular coagulation in patients with acute and chronic leukemia 2015 · Cochrane Headline outcomes only
RR 0.53 [0.05, 5.66]
1 study · 107 participants
Very low

Intervention not reported

Adverse events · Adults (including pregnant women) and children

The review found no eligible studies for this question.

1 finding from 1 review

Strategies to increase the ownership and use of insecticide‐treated bednets to prevent malaria 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Helicopter emergency medical services vs ground emergency medical services

Adverse events · adults (age > 15 years) with major trauma (ISS > 15)

The review found no eligible studies for this question.

1 finding from 1 review

Helicopter emergency medical services for adults with major trauma 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse events · patients with Alzheimer's disease

The intervention showed no clear difference in adverse events (moderate certainty).

1 finding from 1 review

Latrepirdine for Alzheimer's disease 2015 · Cochrane Headline outcomes only
RR 1.03 [0.93, 1.14]
4 studies · 1034 participants
Moderate

Leukoreduced PRBCs vs non‐leukoreduced PRBCs

Adverse events · Patients receiving RBC transfusion

Leukoreduced PRBCs showed no clear difference in adverse events compared with non‐leukoreduced PRBCs (low certainty).

1 finding from 1 review

Leukoreduction for the prevention of adverse reactions from allogeneic blood transfusion 2015 · Cochrane Headline outcomes only
RR 0.81 [0.64, 1.02]
2 studies · 634 participants
Low

MET vs all other therapies

Adverse events · patients with non‐specific low‐back pain (LBP)

The review found no eligible studies for this question.

2 findings from 1 review

Muscle energy technique for non‐specific low‐back pain 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Muscle energy technique for non‐specific low‐back pain 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

MET plus any intervention vs the intervention alone

Adverse events · patients with non‐specific low‐back pain (LBP)

The review found no eligible studies for this question.

2 findings from 1 review

Muscle energy technique for non‐specific low‐back pain 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Muscle energy technique for non‐specific low‐back pain 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

MET plus any intervention vs other therapies plus that intervention

Adverse events · patients with non‐specific low‐back pain (LBP)

The review found no eligible studies for this question.

2 findings from 1 review

Muscle energy technique for non‐specific low‐back pain 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Muscle energy technique for non‐specific low‐back pain 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

MET vs sham MET

Adverse events · patients with non‐specific low‐back pain (LBP)

The review found no eligible studies for this question.

1 finding from 1 review

Muscle energy technique for non‐specific low‐back pain 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse events · participants with low back pain

The review found no eligible studies for this question.

1 finding from 1 review

Pilates for low back pain 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse events · patients with low back pain

The review found no eligible studies for this question.

1 finding from 1 review

Pilates for low back pain 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse events · patients undergoing orthognathic surgery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse events · patients undergoing orthognathic surgery

1 finding from 1 review

Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 70 participants
Low

Preoperative inspiratory muscle training vs usual care, non‐exercise intervention

Adverse events · adult participants undergoing cardiac and major abdominal surgery

1 finding from 1 review

Preoperative inspiratory muscle training for postoperative pulmonary complications in adults undergoing cardiac and… 2015 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 462 participants
Low