Question · asked by 1 review

Leukoreduced PRBCs vs non‐leukoreduced PRBCs: Adverse events

Leukoreduced PRBCs showed no clear difference in adverse events compared with non‐leukoreduced PRBCs (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Leukoreduced PRBCs vs non‐leukoreduced PRBCs
Adverse events · Patients receiving RBC transfusion
Leukoreduced PRBCs showed no clear difference in adverse events compared with non‐leukoreduced PRBCs (low certainty).
Leukoreduction for the prevention of adverse reactions from allogeneic blood transfusion (2015) · Cochrane Headline outcomes only
RR 0.81 [0.64, 1.02]2 studies · 634 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Leukoreduction for the prevention of adverse reactions from allogeneic blood transfusion
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.