Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,918 questions · 5,537 findings · 1,803 reviews

No studies found 1,309 · 23.6%GRADE not reported 440 · 7.9%Very low 1,560 · 28.2%Low 1,292 · 23.3%Moderate 751 · 13.6%High 185 · 3.3%

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Periodontal treatment: scaling and root planing (SRP) plus advice vs Community care: advice only

Adverse events due to periodontal therapy · Patients with cardiovascular disease and chronic periodontitis
1 finding from 1 review

Active stimulation + other intervention vs other intervention alone

Adverse event: lead failure/ displacement · adults with chronic pain

It is very uncertain whether active stimulation + other intervention changes adverse events:lead failure/ displacement compared with other intervention alone (very low certainty).

2 findings from 1 review

Intervention not reported

Adverse events Post‐operative atelectasis · participants with β‐thalassaemia

It is very uncertain whether the intervention changes adverse events Post‐operative atelectasis (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse events 12 months postintervention · adults with refractory glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events 12 months postintervention · adults with refractory glaucoma
1 finding from 1 review

Taxane followed by anthracyclines vs anthracyclines followed by taxane

Grade 3 to 4 neutropenia · adjuvant therapy for early breast cancer

Taxane followed by anthracyclines leads to lower adverse events: neutropenia (grade 3/4) ( compared with anthracyclines followed by taxane (high certainty).

1 finding from 1 review

Taxane followed by anthracyclines vs anthracyclines followed by taxane

Grade 3 to 4 neutropenia · neoadjuvant therapy for early breast cancer

Taxane followed by anthracyclines showed no clear difference in adverse events: neutropenia (grade 3/4) ( compared with anthracyclines followed by taxane (moderate certainty).

1 finding from 1 review