Cochrane · systematic review · CD004634

Follicular flushing during oocyte retrieval in assisted reproductive techniques

Georgiou, EX, Melo, P, Cheong, YC, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library

Gynaecology and Fertility2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 5 · 71.4%Moderate 1 · 14.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Summary of findings table ‐ Aspiration/flush compared to aspiration for women undergoing assisted conception

Population: women undergoing assisted conception
7 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth rate ‐ total
Summary of findings table ‐ Aspiration/flush vs aspiration
OR 0.93 [0.59, 1.46]4 studies · 467 participantsModerate
Downgraded: imprecision
Miscarriage rate ‐ total
Summary of findings table ‐ Aspiration/flush vs aspiration
OR 1.98 [0.18, 22.22]1 study · 164 participantsLow
Downgraded: imprecision
Oocyte yield per woman randomised (normally distributed data)
Summary of findings table ‐ Aspiration/flush vs aspiration
no estimate extracted9 studies · 1239 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Duration of oocyte retrieval (normally distributed data; seconds)
Summary of findings table ‐ Aspiration/flush vs aspiration
no estimate extracted7 studies · 785 participantsLow
Downgraded: risk of bias, inconsistency
Total number of embryos (normally distributed data)
Summary of findings table ‐ Aspiration/flush vs aspiration
no estimate extracted2 studies · 160 participantsLow
Downgraded: risk of bias, inconsistency
Clinical pregnancy rate per woman randomised
Summary of findings table ‐ Aspiration/flush vs aspiration
OR 1.13 [0.85, 1.51]7 studies · 939 participantsLow
Downgraded: risk of bias, imprecision
Adverse events (dichotomous data) ‐ total
Summary of findings table ‐ Aspiration/flush vs aspiration
no estimate extracted3 studies · 3 participantsLow
Downgraded: risk of bias, imprecision