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TCA showed no clear difference in number of dropouts due to adverse events compared with MAOI (low certainty).
SSRIs showed no clear difference in number of dropouts due to adverse events compared with MAOIs (low certainty).
SSRIs showed no clear difference in number of dropouts due to adverse events compared with naSSAs (low certainty).
Treatment of UI after radical: combinations of treatments showed no clear difference in adverse events ‐ PFMT + anal EStim + BFB compared with no treatment (low certainty).
The review found no eligible studies for this question.
It is very uncertain whether trapeziectomy with interpositional arthroplasty (T and IA) changes adverse events Mild to moderate swelling compared with artelon joint resurfacing (very low certainty).
Any growth factor showed no clear difference in adverse events (non‐serious and serious) compared with placebo or no growth factor (low certainty).
It is very uncertain whether PFMT added to drug therapy changes number of women reporting adverse events compared with drug therapy alone (very low certainty).
Summary of findings table ‐ Daratumumab plus standard therapy probably leads to higher serious adverse events (longest available compared with standard therapy (moderate certainty).
It is very uncertain whether pharmacological intervention and non‐invasive brain stimulation… changes adverse events: death (secondary outcome) compared with a pharmacological intervention and sham stimulation or usual care… (very low certainty).
It is very uncertain whether pharmacological interventions changes adverse events: death (secondary outcome) compared with placebo (very low certainty).
It is very uncertain whether summary of findings 2: PLD alone changes overall severe adverse events (grade > 3) compared with other conventional chemotherapy (very low certainty).
Summary of findings 3: PLD with chemotherapy probably leads to higher overall severe adverse events (grade ≥ 3) compared with PLD alone (moderate certainty).
Summary of findings 1: PLD with chemotherapy showed no clear difference in overall severe adverse events (grade ≥ 3) compared with alternative combination chemotherapy (moderate certainty).
It is very uncertain whether summary of findings table ‐ High flow nasal cannula (HFNC) changes adverse events ‐ abdominal overdistention compared with continuous positive airway pressure (CPAP) (very low certainty).
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes adverse events due to periodontal therapy compared with supragingival scaling (plus placebo) (very low certainty).
It is very uncertain whether intravenous ± oral steroids changes adverse events: gastrointestinal bleeding compared with oral steroids alone (very low certainty).
It is very uncertain whether steroids changes adverse events: doubling serum creatinine compared with no specific treatment (very low certainty).