Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,918 questions · 5,537 findings · 1,803 reviews

No studies found 1,309 · 23.6%GRADE not reported 440 · 7.9%Very low 1,560 · 28.2%Low 1,292 · 23.3%Moderate 751 · 13.6%High 185 · 3.3%

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Lifestyle interventions vs placebo or usual care

Adverse events – musculoskeletal · weight reduction in obesity to improve survival in women with endometrial cancer

It is very uncertain whether summary of findings table ‐ Lifestyle intervention changes adverse events – musculoskeletal compared with usual care compared to placebo (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Selective prevention interventions vs control group

Adverse events at study endpoint · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

Adverse events at study endpoint · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Promotion/universal prevention interventions vs control group

Adverse events at study endpoint · preventing mental disorders
2 findings from 1 review

Custom foot orthoses vs shoes

Withdrawals due to adverse events · children with juvenile idiopathic arthritis and flat feet

Custom foot orthoses showed no clear difference in withdrawal due to adverse events compared with shoes (low certainty).

1 finding from 1 review

Prefabricated foot orthoses vs shoes

Withdrawals due to adverse events · children with juvenile idiopathic arthritis and flat feet

Prefabricated foot orthoses showed no clear difference in withdrawal due to adverse events compared with shoes; GRADE not reported.

1 finding from 1 review

Pyronaridine‐artesunate (PY‐AS) vs mefloquine plus artesunate (MQ + AS)

Serious adverse events (42 days) · adults and children with uncomplicated P falciparum malaria

Pyronaridine‐artesunate (PY‐AS) showed no clear difference in serious adverse events (42 days) compared with mefloquine plus artesunate (MQ + AS) (low certainty).

1 finding from 1 review

Pyronaridine‐artesunate (PY‐AS) vs artemether‐lumefantrine (AL)

Serious adverse events (42 days) · adults and children with uncomplicated P falciparum malaria

Pyronaridine‐artesunate (PY‐AS) showed no clear difference in serious adverse events (42 days) compared with artemether‐lumefantrine (AL) (low certainty).

1 finding from 1 review

Summary of findings table ‐ Stem Cell vs placebo or control

Withdrawals due to adverse events · Induction of Remission in Medically Refractory Crohn's Disease

It is very uncertain whether summary of findings table ‐ Stem Cell changes withdrawal due to adverse events compared with placebo or Control (very low certainty).

1 finding from 1 review