What do systematic reviews say?

Alginate dressing vs alternative alginate dressing (Tegagen™ High Gelling)

• Alginate dressings for venous leg ulcers 2015 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Intervention not reported

• Corneal collagen cross‐linking for treating keratoconus 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 3 participants
  GRADE not reported

Cessation of water fluoridation (fluoride removed from the water supply) vs Continued fluoridated water

The review found no eligible studies for this question.

• Water fluoridation for the prevention of dental caries 2015 · Cochrane All outcomes
  No evidence to determine whether cessation of a water fluoridation programme is associated with any harms.
  0 studies
  No studies found

Xylitol wipes (4.2 g/day) vs Control wipes (no xylitol)

• Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes

  12 months
  The authors reported that there were no adverse effects for either group. Zhan 2012.
  1 study · 44 participants
  GRADE not reported

Diazepam gel vs Placebo gel

Diazepam gel showed no clear difference in adverse effects compared with placebo gel (moderate certainty).

• Anticonvulsant therapy for status epilepticus 2014 · Cochrane Headline outcomes only
  RR 1.5 [0.94, 2.37]
  2 studies · 165 participants
  Moderate

Summary of findings ‐ Intravenous lorazepam vs intravenous diazepam

• Anticonvulsant therapy for status epilepticus 2014 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 264 participants
  Very low

Summary of findings ‐ Intravenous lorazepam vs intravenous diazepam/intravenous phenytoin combination

Lorazepam IV showed no clear difference in adverse effects compared with diazepam plus phenytoin IV (moderate certainty).

• Anticonvulsant therapy for status epilepticus 2014 · Cochrane Headline outcomes only
  RR 0.85 [0.63, 1.15]
  2 studies · 370 participants
  Moderate

Brachytherapy vs brachytherapy plus radiotherapy

Brachytherapy showed no clear difference in adverse effects compared with brachytherapy plus radiotherapy (moderate certainty).

• Interventions for dysphagia in oesophageal cancer 2014 · Cochrane Headline outcomes only
  OR 1.17 [0.44, 3.15]
  2 studies · 554 participants
  Moderate

Shengmai vs placebo

• Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 2 participants
  GRADE not reported

Shengmai plus usual treatment vs usual treatment alone

• Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 4 participants
  GRADE not reported

Summary of findings: needle acupuncture vs sham

• Acupuncture for epilepsy 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 120 participants
  GRADE not reported

Summary of findings: needle acupuncture vs phenytoin

• Acupuncture for epilepsy 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 120 participants
  GRADE not reported

Summary of findings: needle acupuncture plus Chinese herbs vs Chinese herbs alone

• Acupuncture for epilepsy 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 120 participants
  GRADE not reported

Health education vs HEALTH EMPOWERMENT EDUCATION

HEALTH EDUCATION led to lower adverse Effects compared with HEALTH EMPOWERMENT EDUCATION; GRADE not reported.

• General physical health advice for people with serious mental illness 2014 · Cochrane Headline outcomes only
  RR 0 [0, 0]
  0 studies · 0 participants
  GRADE not reported

Intervention not reported

The review found no eligible studies for this question.

• Relaxation for perimenopausal and postmenopausal symptoms 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Dual mini-screw implant vs Single mini-screw implant

The review found no eligible studies for this question.

• Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods 2014 · Cochrane All outcomes
  Adverse effects were not reported in any of the studies comparing two types of surgical anchorage
  0 studies
  No studies found

Resin composite restorations containing antibacterial agents vs Non-antibacterial containing composite restorations

The review found no eligible studies for this question.

• Antibacterial agents in composite restorations for the prevention of dental caries 2013 · Cochrane All outcomes
  No studies were included in this review, as we were unable to find any trials directly comparing antibacterial containing composites to other active interventions or controls.
  0 studies
  No studies found

First‐line chemotherapy vs BSC

• Chemotherapy versus best supportive care for extensive small cell lung cancer 2013 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 65 participants
  Very low

Intervention not reported

• Chemotherapy versus best supportive care for extensive small cell lung cancer 2013 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 542 participants
  Moderate

Physiotherapy with traction vs physiotherapy without traction

The review found no eligible studies for this question.

• Traction for low‐back pain with or without sciatica 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found