Question · asked by 0 reviews

Vitamin D plus calcium vs no treatment/placebo (no vitamin or minerals): Pre‐eclampsia

Population
women during pregnancy
Intervention
Vitamin D plus calcium
Comparison
no treatment/placebo (no vitamin or minerals)
Outcome
Pre‐eclampsia

Vitamin D + calcium probably leads to lower pre‐eclampsia (ALL) compared with no treatment/placebo (no vitamin or minerals) (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Vitamin D + calcium vs no treatment/placebo (no vitamin or minerals)
Pre‐eclampsia (ALL) · women during pregnancy
Vitamin D + calcium probably leads to lower pre‐eclampsia (ALL) compared with no treatment/placebo (no vitamin or minerals) (moderate certainty).
Vitamin D supplementation for women during pregnancy (2016) · Cochrane Headline outcomes onlyearlier version CD008873.PUB3, superseded
RR 0.51 [0.32, 0.8]3 studies · 1114 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Vitamin D supplementation for women during pregnancy
2019 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.