Same question across reviews · CL0368
unknown :: Unclassified intervention -> Microbiological/plaque
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
6
Questions
9
current versions
GRADE rated
0
Review overlap (CCA)
0.000
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intervention NR Reduction of preformed S. mutans biofilms · In vitro Postbiotics and Dental Caries: A Systematic Review. (2025) | no estimate extracted | 2 studies | Ungraded |
Intervention NR Plaque index, e-cigarette users versus non-smokers: no significant difference (contrary/null finding) · Ralho (6 of 8 studies); Thiem (1 study) An Umbrella Review of E-Cigarettes' Impact on Oral Microbiota and Biofilm Buildup. (2025) | Qualitative (narrative synthesis) No significant plaque-index difference vs non-smokers | 2 studies | Ungraded |
Intervention NR Bacterial count reduction · AR-assisted toothbrush vs manual toothbrushing The Application of Gamification in Children's Oral Health Management: Systematic Review. (2025) | Narrative (P value) Significant reduction in bacterial count with AR-assisted toothbrush (P<.05) | 1 study | Ungraded |
Intervention NR Inhibition of S. sobrinus growth and biofilm formation (incl. ftf/gtfB/gtfC expression) · In vitro Postbiotics and Dental Caries: A Systematic Review. (2025) | no estimate extracted | 1 study | Ungraded |
Intervention NR Inhibition of mixed-species S. mutans-C. albicans biofilm and C. albicans virulence-gene (HWP1/ALS1/ALS3) downregulation · In vitro (interkingdom) Postbiotics and Dental Caries: A Systematic Review. (2025) | no estimate extracted | 1 study | Ungraded |
Intervention NR Altered cariogenic-biofilm composition/architecture with reduced abundance of cariogenic species · In vitro (multispecies biofilm) Postbiotics and Dental Caries: A Systematic Review. (2025) | no estimate extracted | 1 study | Ungraded |
Intervention NR Change in prevalence of salivary Streptococcus sobrinus · Single study (Stsepetova et al. 2019), erythritol and xylitol vs sorbitol, not pooled Clinical Effects of Sugar Substitutes on Cariogenic Bacteria: A Systematic Review and Meta-Analysis. (2024) | Narrative (no effect size) Erythritol and xylitol significantly reduced the prevalence of salivary S. sobrinus | 1 study | Ungraded |
Intervention NR Cariogenic microbiota counts (Streptococcus mutans, Lactobacillus spp.) · Narrative synthesis: significantly higher in CLP vs controls (Ahluwalia, Lucas, Hassani, Cheng, Sundell) Characterization of the oral microbiota and the relationship of the oral microbiota with the dental and… (2024) | no estimate extracted | 5 studies | Ungraded |
Intervention NR Oral Candida carriage and salivary yeast concentration Impact of Antiretroviral Therapy on Oral Health among Children Living with HIV: A Systematic Review and… (2022) | no estimate extracted | 1 study | Ungraded |