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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
9 questions in 6 reviews · cluster CL0368
current versionsNo studies 0 · 0%Ungraded 9 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intervention NR Reduction of preformed S. mutans biofilms · In vitro Postbiotics and Dental Caries: A Systematic Review. (2025) | no estimate extracted | 2 studies | Ungraded |
Intervention NR Plaque index, e-cigarette users versus non-smokers: no significant difference (contrary/null finding) · Ralho (6 of 8 studies); Thiem (1 study) An Umbrella Review of E-Cigarettes' Impact on Oral Microbiota and Biofilm Buildup. (2025) | Qualitative (narrative synthesis) No significant plaque-index difference vs non-smokers | 2 studies | Ungraded |
Intervention NR Bacterial count reduction · AR-assisted toothbrush vs manual toothbrushing The Application of Gamification in Children's Oral Health Management: Systematic Review. (2025) | Narrative (P value) Significant reduction in bacterial count with AR-assisted toothbrush (P<.05) | 1 study | Ungraded |
Intervention NR Inhibition of S. sobrinus growth and biofilm formation (incl. ftf/gtfB/gtfC expression) · In vitro Postbiotics and Dental Caries: A Systematic Review. (2025) | no estimate extracted | 1 study | Ungraded |
Intervention NR Inhibition of mixed-species S. mutans-C. albicans biofilm and C. albicans virulence-gene (HWP1/ALS1/ALS3) downregulation · In vitro (interkingdom) Postbiotics and Dental Caries: A Systematic Review. (2025) | no estimate extracted | 1 study | Ungraded |
Intervention NR Altered cariogenic-biofilm composition/architecture with reduced abundance of cariogenic species · In vitro (multispecies biofilm) Postbiotics and Dental Caries: A Systematic Review. (2025) | no estimate extracted | 1 study | Ungraded |
Intervention NR Change in prevalence of salivary Streptococcus sobrinus · Single study (Stsepetova et al. 2019), erythritol and xylitol vs sorbitol, not pooled Clinical Effects of Sugar Substitutes on Cariogenic Bacteria: A Systematic Review and Meta-Analysis. (2024) | Narrative (no effect size) Erythritol and xylitol significantly reduced the prevalence of salivary S. sobrinus | 1 study | Ungraded |
Intervention NR Cariogenic microbiota counts (Streptococcus mutans, Lactobacillus spp.) · Narrative synthesis: significantly higher in CLP vs controls (Ahluwalia, Lucas, Hassani, Cheng, Sundell) Characterization of the oral microbiota and the relationship of the oral microbiota with the dental and… (2024) | no estimate extracted | 5 studies | Ungraded |
Intervention NR Oral Candida carriage and salivary yeast concentration Impact of Antiretroviral Therapy on Oral Health among Children Living with HIV: A Systematic Review and… (2022) | no estimate extracted | 1 study | Ungraded |